Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/68895
Type: Artigo de periódico
Title: Human cryptococcosis: relationship of environmental and clinical strains of Cryptococcus neoformans var. neoformans from urban and rural areas
Author: Delgado, ACN
Taguchi, H
Mikami, Y
Myiajy, M
Villares, MCB
Moretti, ML
Abstract: Forty-five clinical and 55 environmental strains of Cryptococcus neoformans var. neoformans from Sao Paulo, Brazil, were tested for their susceptibilities to amphotericin B, fluconazole, itraconazole, and flucytosine by the broth microdilution method according to the National Committee of Clinical Laboratory Standards guidelines. Electrophoretic karyotypes analysis by counter-clamped homogeneous electrophoresis was used to compare their genetic relatedness. Molecular typing revealed three clinical profiles very similar to two environmental profiles and an identical environmental and clinical pro. le. The results showed that human cryptococcosis can be acquired from environmental strains, which had similar minimum inhibitory concentration values to clinical strains, for antifungal agents.
Subject: acquired immuno deficiency syndrome
antifungal susceptibility testing
Cryptococcus neoformans
molecular typing
pigeon droppings
Country: Holanda
Editor: Springer
Rights: fechado
Identifier DOI: 10.1007/s11046-004-9618-4
Date Issue: 2005
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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