Please use this identifier to cite or link to this item:
Type: Artigo de periódico
Title: HR-DOSY and sulfoxide enantiomeric discrimination by cyclodextrin
Author: Borges, RB
Laverde, A
Porto, ALM
Marsaioli, AJ
Abstract: Racemic and chiral ethyl-phenylsulfoxide (solute) and beta -cyclodextrin (chiral selector) were used to compare two NMR methodologies to predict RP-HPLC enantiomeric resolution efficiency. One of them based on the classical approach involving apparent binding constants and complexation-induced chemical shifts at saturation and the other based on C-13 NMR signal splittings (solute and chiral selector in stoichiometric ratio) and HR-DOSY of the same solution. We have concluded that the latter methodology is rather efficient and though more elaborate from the NMR point of view, the results are promising and constitute an alternative method to investigate chiral recognition and other supramolecular phenomena.
Country: Holanda
Editor: Ios Press
Citation: Spectroscopy-an International Journal. Ios Press, v. 14, n. 4, n. 203, n. 213, 2000.
Rights: fechado
Date Issue: 2000
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
WOS000167168600005.pdf126.26 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.