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|Type:||Artigo de periódico|
|Title:||Haptoglobin genotypes in Chagas' disease|
|Abstract:||Objectives: To investigate the existence of an association between haptoglobin (Hp) genotypes and the severity of heart complications in Chagas' disease. Design and methods: Hp genotyping was performed by PCR in 107 Brazilian patients sub-classified in asymptomatic, with mild heart disease and with severe heart disease. Results: Multiple logistic regression (R(2) = 24%) indicated that patients with the Hp1-1 genotype have lower probability of developing the severe heart complications. Conclusion: The Hp polymorphism may influence the clinical evolution of Chagas' disease. (C) 2009 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.|
|Editor:||Pergamon-elsevier Science Ltd|
|Appears in Collections:||Artigos e Materiais de Revistas Científicas - Unicamp|
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