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Type: Artigo de periódico
Title: Haemostatic management of extreme challenges to haemostasis in acquired von Willebrand syndrome
Author: Colella, MP
Duarte, GC
Marques, JFC
De Paula, EV
Abstract: . Acquired von Willebrand syndrome (AVWS) is a rare hemorrhagic condition for which very little information is available regarding the management of extreme challenges to Haemostasis. The AVWS is more common in the elderly, who are frequently exposed to invasive procedures and/or chemotherapy. Haematopoietic stem cell transplantation (HSCT) is a situation in which the haemostatic capacity is challenged by severe thrombocytopaenia, chemotherapy-associated mucosal barrier breakdown and the need for invasive procedures. In our report, we present and discuss the haemostatic management of a patient with AVWS who was refractory to Von Willebrand factor concentrate replacement during the course of an autologous HSCT to treat multiple myeloma. Patients with AVWS are frequently exposed to high-risk haemostatic challenges, and additional information about the haemostatic management of these situations is necessary.
Subject: acquired von Willebrand syndrome
haematopoietic stem cell transplantation
multiple myeloma
Country: EUA
Editor: Wiley-blackwell
Citation: Haemophilia. Wiley-blackwell, v. 18, n. 3, n. e188, n. e191, 2012.
Rights: fechado
Identifier DOI: 10.1111/j.1365-2516.2012.02769.x
Date Issue: 2012
Appears in Collections:Unicamp - Artigos e Outros Documentos

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