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Type: Artigo de periódico
Title: High expression of FMNL1 protein in T non-Hodgkin's lymphomas
Author: Favaro, PMB
Traina, F
Vassallo, J
Brousset, P
Delsol, G
Costa, FF
Saad, STO
Abstract: We recently cloned a novel Formin-fan-lily human gene, denominated human leukocyte formin and posteriorly named as FMNL1 by the HUGO Gene Nomenclature Committee. This gene is overexpressed in lymphoid malignances and is found associated with Akt. Here, we describe the expression of the FMNL1 protein in 54 frozen biopsies of non-Hodgkin's lymphoma (NHL) patients and five reactive lymph nodes. Western blot analysis revealed expression of FMNL1 in all samples studied, although the highest expression was in T-cell NHL (P < 0.05). (c) 2005 Elsevier Ltd. All rights reserved.
Subject: FMNL1
human leukocyte formin
non-Hodgkin's lymphomas
Country: Inglaterra
Editor: Pergamon-elsevier Science Ltd
Citation: Leukemia Research. Pergamon-elsevier Science Ltd, v. 30, n. 6, n. 735, n. 738, 2006.
Rights: fechado
Identifier DOI: 10.1016/j.leukres.2005.10.003
Date Issue: 2006
Appears in Collections:Unicamp - Artigos e Outros Documentos

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