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Type: Artigo de periódico
Title: Global Phylogeny of Shigella sonnei Strains from Limited Single Nucleotide Polymorphisms (SNPs) and Development of a Rapid and Cost-Effective SNP-Typing Scheme for Strain Identification by High-Resolution Melting Analysis
Author: Sangal, V
Holt, KE
Yuan, JF
Brown, DJ
Filliol-Toutain, I
Weill, FX
Kim, DW
da Silveira, WD
Pickard, D
Thomson, NR
Parkhill, J
Yu, J
Abstract: The current Shigella sonnei pandemic involves geographically associated, multidrug-resistant clones. This study has demonstrated that S. sonnei phylogeny can be accurately defined with limited single nucleotide polymorphisms (SNPs). By typing 6 informative SNPs using a high-resolution melting (HRM) assay, major S. sonnei lineages/sublineages can be identified as defined by whole-genome variation.
Country: EUA
Editor: Amer Soc Microbiology
Citation: Journal Of Clinical Microbiology. Amer Soc Microbiology, v. 51, n. 1, n. 303, n. 305, 2013.
Rights: aberto
Identifier DOI: 10.1128/JCM.02238-12
Date Issue: 2013
Appears in Collections:Unicamp - Artigos e Outros Documentos

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