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Type: Artigo de periódico
Title: Genotype frequencies at codon 129 of the Prion Protein Gene in Brazil: implications in susceptibility to variant Creutzfeldt-Jakob disease compared to European and Asian populations
Author: de Paula, EV
Addas-Carvalho, M
Costa, DSP
Saad, STO
Gilli, SCO
Abstract: A polymorphism at codon 129 of the prion protein gene has been shown to confer genetic susceptibility to prion diseases, and to influence the epidemic course of variant Creutzfeldt--Jakob disease. We employed a PCR-endonuclease digestion-based assay to investigate this genetic trait in Brazil, and then compared our results to previously published data from several European and Asian countries.
Subject: codon 129
genotype frequencies
prion diseases
Country: EUA
Editor: Springer
Citation: European Journal Of Epidemiology. Springer, v. 20, n. 7, n. 593, n. 595, 2005.
Rights: fechado
Identifier DOI: 10.1007/s10654-005-7455-5
Date Issue: 2005
Appears in Collections:Unicamp - Artigos e Outros Documentos

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