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dc.contributor.CRUESPUniversidade Estadual de Campinaspt_BR
dc.typeArtigo de periódicopt_BR
dc.titleFurther bioactive piperidine alkaloids from the flowers and green fruits of Cassia spectabilispt_BR
dc.contributor.authorViegas, Cpt_BR
dc.contributor.authorBolzani, VDpt_BR
dc.contributor.authorFurlan, Mpt_BR
dc.contributor.authorBarreiro, EJpt_BR
dc.contributor.authorYoung, MCMpt_BR
dc.contributor.authorTomazela, Dpt_BR
dc.contributor.authorEberlin, MNpt_BR
unicamp.author.emailbolzaniv@iq.unesp.brpt_BR
unicamp.authorUniv Estadual Paulista, UNESP, Inst Quim, BR-14800900 Araraquara, SP, Brazil Univ Fed Rio de Janeiro, Fac Farm, BR-21944190 Rio De Janeiro, Brazil Inst Bot, IBt, Seccao Fisiol & Bioquim Plantas, BR-01061970 Sao Paulo, Brazil Univ Estadual Campinas, Inst Quim, UNICAMP, BR-13083970 Campinas, SP, Brazilpt_BR
dc.subject.wosMedicinal-plantspt_BR
dc.subject.wosHepatoprotective Activitypt_BR
dc.subject.wosDerivativespt_BR
dc.subject.wosLeavespt_BR
dc.description.abstractThe flowers of Cassia spectabilis yielded three new piperidine alkaloids, (-)-3-O-acetylspectaline (1), (-)-7-hydroxyspectaline (2), and iso-6-spectaline (3), together with the known (-)-spectaline (4). The green fruits of this plant were also investigated, resulting in the isolation of 1 and 4. Their structures were elucidated using a combination of multidimensional NMR and MS techniques, and relative stereochemistries were established by NOESY correlations and analysis of coupling constants. The DNA-damaging activity of these compounds was evaluated using a mutant yeast, Saccharomyces cerevisiae, assay.pt
dc.relation.ispartofJournal Of Natural Productspt_BR
dc.relation.ispartofabbreviationJ. Nat. Prod.pt_BR
dc.publisher.cityWashingtonpt_BR
dc.publisher.countryEUApt_BR
dc.publisherAmer Chemical Socpt_BR
dc.date.issued2004pt_BR
dc.date.monthofcirculationMAYpt_BR
dc.identifier.citationJournal Of Natural Products. Amer Chemical Soc, v. 67, n. 5, n. 908, n. 910, 2004.pt_BR
dc.language.isoenpt_BR
dc.description.volume67pt_BR
dc.description.issuenumber5pt_BR
dc.description.firstpage908pt_BR
dc.description.lastpage910pt_BR
dc.rightsfechadopt_BR
dc.sourceWeb of Sciencept_BR
unicamp.cruespUNESPpt_BR
dc.identifier.issn0163-3864pt_BR
dc.identifier.wosidWOS:000221804700034pt_BR
dc.identifier.doi10.1021/np0303963pt_BR
dc.date.available2014-11-13T23:42:25Z
dc.date.available2015-11-26T16:02:59Z-
dc.date.accessioned2014-11-13T23:42:25Z
dc.date.accessioned2015-11-26T16:02:59Z-
dc.description.provenanceMade available in DSpace on 2014-11-13T23:42:25Z (GMT). No. of bitstreams: 1 WOS000221804700034.pdf: 43882 bytes, checksum: 5b3d73d5eb2796b0992fa80b0fbfab69 (MD5) Previous issue date: 2004en
dc.description.provenanceMade available in DSpace on 2015-11-26T16:02:59Z (GMT). No. of bitstreams: 2 WOS000221804700034.pdf: 43882 bytes, checksum: 5b3d73d5eb2796b0992fa80b0fbfab69 (MD5) WOS000221804700034.pdf.txt: 18213 bytes, checksum: 6b77878af8791358d911987c5100ab8a (MD5) Previous issue date: 2004en
dc.identifier.urihttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/67701pt_BR
dc.identifier.urihttp://www.repositorio.unicamp.br/handle/REPOSIP/67701
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/67701-
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