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Type: Artigo de periódico
Title: Forearm bone density in long-term users of oral combined contraceptives and depot medroxyprogesterone acetate
Author: Perrotti, M
Bahamondes, L
Petta, C
Castro, S
Abstract: Objective: To compare the bone mineral density of users of combined oral contraceptives (OC) or depot medroxyprogesterone acetate (depot-MPA) with women who have never used a hormonal contraceptive method. Design: Cross-sectional study. Setting: Academic tertiary-care hospital. Patient(s): A total of 189 women, aged 30 to 34 years old, were allocated to three groups: 63 who had used OC for at least 2 years; 63 who had used depot-MPA for at least 2 years; and 63 control women who had never used hormonal contraceptives. Intervention(s): Each woman's bone mineral density (BMD) was evaluated at the distal and ultradistal section of the radius of the nondominant forearm by the use of single x-ray absorptiometry. Main Outcome Measure(s): We obtained BMD measurements for each participant. Result(s): Independent of the period of use and the section of the forearm studied, we found no difference in BMD for OC or depot-MPA users when compared to women who had never used hormonal contraceptive methods. In addition, BMD was similar between OC users and depot-MPA users. The multiple linear regression analysis showed that the variables associated with BMD were weight, number of pregnancies, and the woman's occupation. Conclusion(s): Women aged 30 to 34 years who have used OC or depot-NIPA have similar BMD as control women. These findings suggest that the use of OC or depot-MPA does not affect the BMD of women in this age group. (Fertil Steril(R) 2001;76:469-73. (C) 2001 by American Society for Reproductive Medicine.).
Subject: hormonal contraceptives
bone density
depot medroxyprogesterone acetate
Country: EUA
Editor: Elsevier Science Inc
Citation: Fertility And Sterility. Elsevier Science Inc, v. 76, n. 3, n. 469, n. 473, 2001.
Rights: fechado
Identifier DOI: 10.1016/S0015-0282(01)01936-7
Date Issue: 2001
Appears in Collections:Unicamp - Artigos e Outros Documentos

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