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Type: Artigo de periódico
Title: Fine needle aspiration biopsy for improving the diagnostic accuracy of cut needle biopsy of focal liver lesions
Author: Franca, AVC
Valerio, HMG
Trevisan, M
Escanhoela, C
Seva-Pereira, T
Zucoloto, S
Martinelli, A
Soares, EC
Abstract: OBJECTIVE: To determine the value of fine needle aspiration biopsy (FNAB) in comparison to cut needle biopsy (CNB) for the diagnosis of malignancy of focal liver lesions. STUDY DESIGN: A retrospective analysis was conducted on 68 FNAB and 49 CNB procedures performed on 62 patients with focal liver lesions. RESULTS: Cytology permitted a diagnosis of the lesion in 78% of cases. When punctures with insufficient material were excluded (11), the diagnostic accuracy of FNAB was 93%. For the 49 patients who underwent both procedures, FNAB and CNB had the same diagnostic accuracy, 78%, when considered separately and of 88% when considered in combination. Sensitivity, specificity and positive predictive value were similar for the 2 techniques. The negative predictive value was 64% for FNAB and CNB used separately and reached 78% when the 2 techniques were combined. There were no complications during the execution of FNAB and CNB. CONCLUSION: FNAB is an effective and safe method for the diagnosis of focal hepatic lesions, with diagnostic accuracy similar to that of CNB. When the 2 techniques are combined, the accuracy of the diagnosis of malignancy of focal liver lesions increases.
Subject: liver cancer
liver neoplasms
aspiration biopsy
cut needle biopsy
focal liver lesions
Country: EUA
Editor: Sci Printers & Publ Inc
Citation: Acta Cytologica. Sci Printers & Publ Inc, v. 47, n. 3, n. 332, n. 336, 2003.
Rights: fechado
Identifier DOI: 10.1159/000326529
Date Issue: 2003
Appears in Collections:Unicamp - Artigos e Outros Documentos

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