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|Type:||Artigo de periódico|
|Title:||Faster thrombin generation in women with polycystic ovary syndrome compared with healthy controls matched for age and body mass index|
|Author:||de Mendonca-Louzeiro, MRMF|
|Abstract:||Objective: To evaluate hemostatic markers in women with polycystic ovary syndrome (PCOS) compared with healthy controls matched for age and body mass index. Design: Cross-sectional study. Setting: Tertiary teaching hospital. Patient(s): Forty-five women with PCOS and 45 controls paired for age (+/- 2 years) and body mass index (+/- 2 kg/m(2)). Intervention(s): Clinical evaluation and venipuncture. Main Outcome Measure(s): Thrombin activatable fibrinolysis inhibitor, D-dimer, plasminogen activator inhibitor-1, and the thrombin generation test. Result(s): Thrombin generation lag-time was significantly shorter in women with PCOS compared with controls. The other hemostatic parameters were similar in both groups. Conclusion(s): Thrombin generation is faster in young and overweight women with PCOS, suggesting a greater risk of hypercoagulability. (c) 2013 by American Society for Reproductive Medicine.|
|Subject:||Polycystic ovary syndrome|
|Editor:||Elsevier Science Inc|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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