Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/66795
Type: Artigo de periódico
Title: Faster thrombin generation in women with polycystic ovary syndrome compared with healthy controls matched for age and body mass index
Author: de Mendonca-Louzeiro, MRMF
Annichino-Bizzacchi, JM
Magna, LA
Quaino, SKP
Benetti-Pinto, CL
Abstract: Objective: To evaluate hemostatic markers in women with polycystic ovary syndrome (PCOS) compared with healthy controls matched for age and body mass index. Design: Cross-sectional study. Setting: Tertiary teaching hospital. Patient(s): Forty-five women with PCOS and 45 controls paired for age (+/- 2 years) and body mass index (+/- 2 kg/m(2)). Intervention(s): Clinical evaluation and venipuncture. Main Outcome Measure(s): Thrombin activatable fibrinolysis inhibitor, D-dimer, plasminogen activator inhibitor-1, and the thrombin generation test. Result(s): Thrombin generation lag-time was significantly shorter in women with PCOS compared with controls. The other hemostatic parameters were similar in both groups. Conclusion(s): Thrombin generation is faster in young and overweight women with PCOS, suggesting a greater risk of hypercoagulability. (c) 2013 by American Society for Reproductive Medicine.
Subject: Polycystic ovary syndrome
hemostatic markers
coagulation
fibrinolysis
venous thrombosis
Country: EUA
Editor: Elsevier Science Inc
Rights: fechado
Identifier DOI: 10.1016/j.fertnstert.2013.01.105
Date Issue: 2013
Appears in Collections:Unicamp - Artigos e Outros Documentos

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