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dc.contributor.CRUESPUniversidade Estadual de Campinaspt_BR
dc.typeArtigo de periódicopt_BR
dc.titleExpression of neuronal isoform of nitric oxide synthase in spinal neurons of neonatal rats after sciatic nerve transectionpt_BR
dc.contributor.authorRogerio, Fpt_BR
dc.contributor.authorTeixeira, SApt_BR
dc.contributor.authorQueiroz, LDpt_BR
dc.contributor.authorDe Nucci, Gpt_BR
dc.contributor.authorLangone, Fpt_BR
unicamp.authorUNICAMP, State Univ Campinas, Dept Physiol & Biophys, BR-13083970 Campinas, SP, Brazil UNICAMP, State Univ Campinas, Dept Pharmacol, BR-13083970 Campinas, SP, Brazil UNICAMP, State Univ Campinas, Dept Pathol, BR-13083970 Campinas, SP, Brazilpt_BR
dc.subjectnitric oxide synthasept_BR
dc.subjectneonatal ratpt_BR
dc.subjectmotoneuronpt_BR
dc.subjectsciatic nervept_BR
dc.subjectaxotomypt_BR
dc.subjectneuronal deathpt_BR
dc.subjectspinal neuronspt_BR
dc.subject.wosNadph-diaphorase Activitypt_BR
dc.subject.wosNeurotrophic Factorpt_BR
dc.subject.wosRoot Avulsionpt_BR
dc.subject.wosCell-deathpt_BR
dc.subject.wosMotoneuronspt_BR
dc.subject.wosCordpt_BR
dc.subject.wosSurvivalpt_BR
dc.subject.wosInjurypt_BR
dc.subject.wosDependencept_BR
dc.subject.wosApoptosispt_BR
dc.description.abstractMotoneuron death induced by sciatic nerve transection in neonatal rats has been related to induction of the neuronal isoform of nitric oxide synthase (nNOS), a diaphorase of which one of the cofactors is nicotinamide adenine dinucleotide phosphate (NADPH). We transected the sciatic nerve of neonatal rats (P2) and examined nNOS expression by immunostaining in neurons of the sciatic pool and of other spinal levels on the 5th day after surgery. No correspondence was observed between the surviving motoneurons and nNOS positive cells. The appearance and distribution of nNOS positive neurons at all spinal levels and laminae were similar to those of adult animals. These results are at variance with previous studies which showed correlation between motoneuron loss after axotomy and number of NADPH-diaphorase positive motoneurons after sciatic transection. (C) 2001 Published by Elsevier Science Ireland Ltd.pt
dc.relation.ispartofNeuroscience Letterspt_BR
dc.relation.ispartofabbreviationNeurosci. Lett.pt_BR
dc.publisher.cityClarept_BR
dc.publisher.countryIrlandapt_BR
dc.publisherElsevier Sci Ireland Ltdpt_BR
dc.date.issued2001pt_BR
dc.date.monthofcirculation41456pt_BR
dc.identifier.citationNeuroscience Letters. Elsevier Sci Ireland Ltd, v. 307, n. 2, n. 61, n. 64, 2001.pt_BR
dc.language.isoenpt_BR
dc.description.volume307pt_BR
dc.description.issuenumber2pt_BR
dc.description.firstpage61pt_BR
dc.description.lastpage64pt_BR
dc.rightsfechadopt_BR
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policypt_BR
dc.sourceWeb of Sciencept_BR
dc.identifier.issn0304-3940pt_BR
dc.identifier.wosidWOS:000169785800001pt_BR
dc.identifier.doi10.1016/S0304-3940(01)01931-0pt_BR
dc.date.available2014-11-18T03:46:14Z
dc.date.available2015-11-26T16:50:42Z-
dc.date.accessioned2014-11-18T03:46:14Z
dc.date.accessioned2015-11-26T16:50:42Z-
dc.description.provenanceMade available in DSpace on 2014-11-18T03:46:14Z (GMT). No. of bitstreams: 1 WOS000169785800001.pdf: 490479 bytes, checksum: 9b06cd30aa9b6573eb0eb42767582f7c (MD5) Previous issue date: 2001en
dc.description.provenanceMade available in DSpace on 2015-11-26T16:50:42Z (GMT). No. of bitstreams: 2 WOS000169785800001.pdf: 490479 bytes, checksum: 9b06cd30aa9b6573eb0eb42767582f7c (MD5) WOS000169785800001.pdf.txt: 17619 bytes, checksum: 441017635215de6df391da406e0f220b (MD5) Previous issue date: 2001en
dc.identifier.urihttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/66486pt_BR
dc.identifier.urihttp://www.repositorio.unicamp.br/handle/REPOSIP/66486
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/66486-
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