Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/66466
Type: Artigo de periódico
Title: Expression of collagen and elastic fibers in duct-ligated submandibular glands of mice
Author: Zaia, AA
DellaColetta, R
Almeida, OP
Line, SRP
Abstract: Atrophy of salivary glands may occur by ductal obstruction caused by calculus, infection or neoplastic processes, or as consequence of systemic diseases and aging. In the present work, we have used histochemical methods to study the expression of elastic and collagen fibers during experimental atrophy of the submandibular gland of mice. Glandular atrophy was accompanied by a rapid increase in collagen deposition in both septal and intralobular regions. The expression of elastic fibers was not significantly altered during atrophy; a discrete increase of elastic fibers was noted only around ductal structures. The results showed that experimental ductal obstruction is a useful in vivo model to study molecular events that take part in the remodeling of the extracellular matrix during atrophy of salivary glands.
Subject: salivary glands
atrophy
collagen
elastic fiber
Country: Dinamarca
Editor: Munksgaard Int Publ Ltd
Rights: fechado
Identifier DOI: 10.1111/j.1600-0722.1996.tb00153.x
Date Issue: 1996
Appears in Collections:Unicamp - Artigos e Outros Documentos

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