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Type: Artigo de periódico
Title: Evaluation of antimicrobial effectiveness of C-8 xylitol monoester as an alternative preservative for cosmetic products
Author: Amaral, LFB
Camilo, NS
Pereda, MDCV
Levy, CE
Moriel, P
Mazzola, PG
Abstract: Xylitol is a natural sugar derived from plants, fruits and vegetables, whose antimicrobial properties are described in the literature. This study aimed to evaluate the antimicrobial effectiveness of C-8 xylitol monoester, for its use as a preservative in cosmetic formulations. The minimum inhibitory concentration (MIC) was determined by the broth macrodilution method, and the antimicrobial effectiveness of C-8 xylitol monoester was determined by using challenge test method. The results obtained in the determination of minimum inhibitory concentration are between 1.0% and 1.25% for Staphylococcus aureus, Escherichia coli and Candida albicans and between 1.0% and 1.5% for Pseudomonas aeruginosa and Aspergillus niger. The amount of 1% of C-8 xylitol monoester was added to the lotion used in the challenge test, observing a rapid decline in the number of CFU g(-1) in stages of evaluation after contamination of the product by all bacteria. The same occurs in relation to C. albicans, which shows a 90% reduction in the number of CFU g(-1). Regarding A. niger, similar reduction is observed when pH value of the lotion is adjusted from 5.5 to 7.0. The results indicate that under the tests conditions, C-8 xylitol monoester has antimicrobial activity and could be considered as an alternative preservative for cosmetic formulations.
Subject: contamination
cosmetic products
xylitol monoester
Country: EUA
Editor: Wiley-blackwell
Citation: International Journal Of Cosmetic Science. Wiley-blackwell, v. 33, n. 5, n. 391, n. 397, 2011.
Rights: fechado
Identifier DOI: 10.1111/j.1468-2494.2010.00633.x
Date Issue: 2011
Appears in Collections:Unicamp - Artigos e Outros Documentos

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