Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/65373
Type: Artigo de periódico
Title: Efficient synthesis of a new aminoazasugar and dihydroxyprolines from an endocyclic enecarbamate
Author: Pohlit, AM
Correia, CRD
Abstract: A novel procedure for the synthesis of trans-2,3-(2-aminomethyl)-cis-3,4-dihydroxypyrrolidine (a new aminoazasugar) and cis-2,3- and trans-2,3-cis-3,4-dihydroxyprolines is presented. Starting from the known endocyclic enecarbamate 1-carbobenzyloxy-2-pyrroline, the above compounds were efficiently synthesized in 6 or 7 steps in good overall yields. In the key step, trans-2,3-(1-carbobenzyloxy)-cis-3,4-diacetyloxy-2-methoxypyrrolidine underwent Lewis acid promoted cyanation, presumably via the corresponding N-acyliminium ion.
Country: Inglaterra
Editor: Pergamon-elsevier Science Ltd
Rights: fechado
Date Issue: 1997
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.