Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/65307
Type: Artigo de periódico
Title: NEUROPSYCHIATRIC MANIFESTATIONS OF SYSTEMIC LUPUS-ERYTHEMATOSUS - THE VALUE OF ANTICARDIOLIPIN, ANTIGANGLIOSIDES AND ANTIGALACTOCEREBROSIDES ANTIBODIES
Author: COSTALLAT, LTL
DEOLIVEIRA, RM
SANTIAGO, MB
COSSERMELLI, W
SAMARA, AM
Abstract: In an attempt to find a serological marker for neuropsychiatric manifestations (NPM) of SLE, sera from 66 patients (classified in three groups, according to their NPM - defined, probable and without NPM) were analysed by ELISA for IgG and IgM anticardiolipin, antigangliosides and antigalactocerebrosides antibodies. A strong correlation was found between IgM antigangliosides and antigalactocerebrosides antibodies and NPM, but not with IgG class. IgM and IgG antibodies anticardiolipin were not correlated with NPM in this study. Both IgM antigangliosides and antigalactocerebrosides antibodies disappeared in seven patients with definite but clinically inactive NPM. The analysis of these autoantibodies showed an important role predictive for NPM in SLE; the negative test decreases the chance of the NPM.
Subject: SLE
ANTICARDIOLIPIN
ANTIGANGLIOSIDES
NEUROPSYCHIATRIC MANIFESTATIONS
Country: Bélgica
Editor: Royal Belg Rheumatol Soc
Rights: fechado
Identifier DOI: 10.1007/BF02030510
Date Issue: 1990
Appears in Collections:Unicamp - Artigos e Outros Documentos

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