Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/65135
Type: Artigo de periódico
Title: Electrochemical and spectroscopic evidences of the interaction between DNA and Pt(II)(dppf)-complex
Author: Mello, LD
Ribeiro, ES
Kubota, LT
Elmroth, SKC
Pereira, RMS
Abstract: The interaction of Pt(II)(dppf)-complex, namely [Pt(dppf)(H(2)O)(2)](2+) with DNA was investigated by DPV and (1)H-NMR techniques. The results showed that the interaction process has been characterized by changes in the electrochemical parameters of both compounds and the formation of a new anodic current peak close to the anodic current peak of the [Pt(dppf)(H(2)O)(2)](2+). In addition, the (1)H-NMR spectra show that the coordination of Pt(II)(dppf)-complex to dsDNA occurs via N(7) of guanine. Others parameters like pH and ionic strength that affect the interaction process were also investigated.
Subject: DNA
Platinum
Transition metal complexes
DNA-metal complex interaction
Country: Holanda
Editor: Springer
Rights: fechado
Identifier DOI: 10.1007/s10534-008-9175-2
Date Issue: 2009
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
WOS000264546600020.pdf383.49 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.