Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/64890
Type: Artigo de periódico
Title: Enteropathic arthritis in Brazil: data from the Brazilian registry of spondyloarthritis
Author: Resende, GG
Lanna, CCD
Bortoluzzo, AB
Goncalves, CR
Sampaio-Barros, PD
da Silva, JAB
Ximenes, AC
Bertolo, MB
Ribeiro, SLE
Keiserman, M
Menin, R
Skare, TL
Carneiro, S
Azevedo, VF
Vieira, WP
Albuquerque, EN
Bianchi, WA
Bonfiglioli, R
Campanholo, C
Carvalho, HMS
Costa, IP
Duarte, AP
Kohem, CL
Leite, N
Lima, SAL
Meirelles, ES
Pereira, IA
Pinheiro, MM
Polito, E
Rocha, FAC
Santiago, MB
Sauma, MDLC
Valim, V
Abstract: Inflammatory bowel diseases (Crohn's disease and ulcerative rectocolitis) have extraintestinal manifestations 25% of the patients, with the most common one being the enteropathic arthritis. Methods: Prospective, observational, multicenter study with patients from 29 reference centers participating in the Brazilian Registry of Spondyloarthritis (RBE), which incorporates the RESPONDIA (Ibero-American Registry of Spondyloarthritis) group. Demographic and clinical data were collected from 1472 patients and standardized questionnaires for the assessment of axial mobility, quality of life, enthesitic involvement, disease activity and functional capacity were applied. Laboratory and radiographic examinations were performed. The aim of this study is to compare the clinical, epidemiological, genetic, imaging, treatment and prognosis characteristics of patients with enteropathic arthritis with other types of spondyloarthritis in a large Brazilian cohort. Results: A total of 3.2% of patients were classified as having enteroarthritis, 2.5% had spondylitis and 0.7%, arthritis (peripheral predominance). The subgroup of individuals with enteroarthritis had a higher prevalence in women (P < 0.001), lower incidence of inflammatory axial pain (P < 0.001) and enthesitis (P = 0.004). HLA-B27 was less frequent in the group with enteroarthritis (P = 0.001), even when considering only those with the pure axial form. There was a lower prevalence of radiographic sacroiliitis (P = 0.009) and lower radiographic score (BASRI) (P = 0.006) when compared to patients with other types of spondyloarthritis. They also used more corticosteroids (P < 0.001) and sulfasalazine (P < 0.001) and less nonsteroidal anti-inflammatory drugs (P < 0.001) and methotrexate (P = 0.001). Conclusion: There were differences between patients with enteroarthritis and other types of spondyloarthritis, especially higher prevalence of females, lower frequency of HLA-B27, associated with less severe axial involvement. (C) 2013 Elsevier Editora Ltda. All rights reserved.
Subject: Enteropathic arthritis
Crohn's Disease
Ulcerative rectocolitis
Registry studies
Country: EUA
Editor: Elsevier Science Inc
Rights: fechado
Identifier DOI: 10.1016/j.rbre.2013.04.001
Date Issue: 2013
Appears in Collections:Unicamp - Artigos e Outros Documentos

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