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Type: Artigo de periódico
Title: Endoscopic Laser Dichorionization of the Placenta in the Treatment of Severe Twin-Twin Transfusion Syndrome
Author: Peralta, CFA
Molina, FS
Gomez, LF
Bennini, JR
Neto, OG
Barini, R
Abstract: Objectives: To describe the results of a technique of laser ablation of placental vessels in the treatment of severe twin-twin transfusion syndrome (TTTS), which is characterized by separation of the fetoplacental vascular territories and dichorionization of the placenta. Patients and Methods: Descriptive analysis of TTTS cases treated with the endoscopic laser dichorionization of the placenta (ELDP) procedure. The variables evaluated were the occurrence of reversal of the donor-recipient phenotype, persistence of TTTS or twin anemia-polycythemia sequence (TAPS); gestational age at delivery; discharge from the hospital of at least 1 or 2 live neonates, and incidence of neurological alterations among survivors. Results: 67 patients were treated with the ELDP procedure. There was no persistence of TITS, reversal of the donor-recipient phenotype or TAPS. The median gestational age at delivery was 33.0 (23.6-37.7) weeks. The rate of discharge from the hospital of at least 1 or 2 live neonates was 88.2% (67/76) and 71.1% (54/76), respectively. Among survivors, 17 (17/121 = 14.0%) children presented with neurodevelopmental alterations during clinical follow-up. Conclusions: The major contribution of this study was the demonstration that the ELDP technique appears to be associated with a low risk of persistence or recurrence of TTTS and TAPS. (C) 2013 S. Karger AG, Basel
Subject: Twin pregnancy complication
Twin-twin transfusion syndrome
Twin oligo-polyhydramnios sequence
Twin anemia-polycythemia sequence
Laser photocoagulation of placental vessels
Fetal therapy
Country: Suíça
Editor: Karger
Citation: Fetal Diagnosis And Therapy. Karger, v. 34, n. 4, n. 206, n. 210, 2013.
Rights: fechado
Identifier DOI: 10.1159/000354898
Date Issue: 2013
Appears in Collections:Unicamp - Artigos e Outros Documentos

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