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Type: Artigo de periódico
Title: Enantioselective syntheses of (R)- and (S)-argentilactone and their cytotoxic activities against cancer cell lines
Author: de Fatima, A
Kohn, LK
Antonio, MA
de Carvalho, JE
Pilli, RA
Abstract: Concise total syntheses of (R)- and (S)-argentilactone have been developed via enantioselective catalytic allylation (ECA) and ring-closing metathesis pathways (four steps, 39% overall yield and 82-84% ee) from 2-octynal and their in vitro activity against cancer cells is described. (C) 2004 Elsevier Ltd. All rights reserved.
Subject: argentilactone
asymmetric synthesis
cytotoxic activity
cancer cell
Country: Inglaterra
Editor: Pergamon-elsevier Science Ltd
Citation: Bioorganic & Medicinal Chemistry. Pergamon-elsevier Science Ltd, v. 12, n. 20, n. 5437, n. 5442, 2004.
Rights: fechado
Identifier DOI: 10.1016/j.bmc.2004.07.044
Date Issue: 2004
Appears in Collections:Unicamp - Artigos e Outros Documentos

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