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|Type:||Artigo de periódico|
|Title:||Effect of mutations within the Cys-rich region of potyvirus helper component-proteinase on self-interaction|
|Abstract:||The first similar to 60 amino acids of the N-terminal part of the potyvirus helper component-proteinase (HC-Pro) include highly conserved residues comprising a Cys-rich region. In the present study, the domain in Potato virus Y sufficient for self-interaction was mapped using the yeast two-hybrid system to the 83 N-terminal amino acids of HC-Pro. Mutations in the conserved His and two Cys residues within the Cys-rich region have a strong debilitating effect on self-interaction when introduced in the full-length HC-Pro, but not when introduced in the N-terminal fragment.|
|Editor:||Soc General Microbiology|
|Citation:||Journal Of General Virology. Soc General Microbiology, v. 80, n. 2809, n. 2812, 1999.|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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