Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/64136
Type: Artigo
Title: Effects of different protocol doses of low power gallium-aluminum-arsenate (Ga-Al-As) laser radiation (650 nm) on carrageenan induced rat paw ooedema
Title Alternative: 
Author: Albertini, R.
Aimbire, F.S.C.
De Nucci, G.
Castro-Faria-Neto, H.C.
Antunes, E.
Teixeira, S.A.
Cogo, J.C.
Correa, F.I.
Lopes-Martins, R.A.B.
Zangaro, R.A.
Ribeiro, W.
Abstract: The purpose of the present study was to investigate the effect of the low power laser therapy on the acute inflammatory process. Male Wistar rats were used. The rat paw oedema was induced by sub-plantar injection of carrageenan, the paw volume was measured before and I 2 3 and 4 h after the injection using a hydroplethysmometer. To investigate the mechanism action of the Ga-Al-As laser on inflammatory oedema, parallel studies were performed using adrenallectomized rats or rats treated with sodium diclofenac. Different laser irradiation protocols were employed for specific energy densities (EDs), exposure times and repetition rates. The rats were irradiated with the Ga-Al-As laser during 80 s each hour. The ED that produced an anti-inflammatory effect were 1 and 2.5 J/cm(2), reducing the oedema by 27% (P < 0.05) and 45.4% (P < 0.01), respectively. The ED of 2.5 J/cm(2) produced anti-inflammatory effects similar to those produced by the cyclooxigenase inhibitor sodium diclofenac at a dose of 1 mg/kg. In adrenalectomized animals, the laser irradiation failed to inhibit the oedema. Our results suggest that low power laser irradiation possibly exerts its anti-inflammatory effects by stimulating the release of adrenal corticosteroid hormones
metadata.dc.description.abstractalternative: 
Subject: Inflamação
Lasers
Carragenina
Diclofenaco
Country: Holanda
Editor: Elsevier
Citation: Journal Of Photochemistry And Photobiology B-biology. Elsevier Science Sa, v. 74, n. 41700, n. 101, n. 107, 2004.
Rights: fechado
Identifier DOI: 10.1016/j.jphotobiol.2004.03.002
Address: https://www.sciencedirect.com/science/article/pii/S1011134404000363
Date Issue: 2004
Appears in Collections:FCM - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
000221917900005.pdf287.33 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.