Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/64123
Type: Artigo de periódico
Title: Effects of Creatine Supplementation on Glucose Uptake in Rats Submitted to Exercise Training
Author: Freire, TO
Gualano, B
Leme, MD
Polacow, VO
Lancha, AH
Abstract: Recently, studies have suggested that creatine supplementation can modulate glucose homeostasis by increasing glucose uptake in peripheral tissues. The aim of this study was to investigate the effects of creatine supplementation on glucose tolerance, muscle and hepatic glycogen content in rats submitted or not to physical activity for four and eight weeks. Wistar rats were divided in two groups: four and eight weeks of intervention. Afterwards, each group was subdivided in four subgroups, according to supplement intake and exercise: Sedentary Control; Trained Control; Supplemented Sedentary; and Supplemented Trained. The animals had free access to water and chow and the supplemented groups had two % of their diet as creatine monohydrated. The exercise groups swam for 40 minutes a day, four days a week, with two to five % of their body weight attached to their chests. After four and eight weeks, oral glucose tolerance tests were performed and both hepatic and muscle glycogen were determined. No significant differences were observed between groups on glucose tolerance and glycogen content in muscle and hepatic tissue. This study shows that creatine supplementation does not influence neither glucose tolerance nor glycogen concentrations in rats submitted or not to physical activity for four and eight weeks.
Subject: glycine
N-(aminoiminomethyl)-N-methyl-
physical fitness
blood glucose
Country: Brasil
Editor: Soc Brasileira Med Esporte
Rights: aberto
Date Issue: 2008
Appears in Collections:Unicamp - Artigos e Outros Documentos

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