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dc.contributor.CRUESPUniversidade Estadual de Campinaspt_BR
dc.typeArtigo de periódicopt_BR
dc.titleEffects of a leucine-rich diet on body composition during nutritional recovery in ratspt_BR
dc.contributor.authorVentrucci, Gpt_BR
dc.contributor.authorSilva, LGRpt_BR
dc.contributor.authorMello, MARpt_BR
dc.contributor.authorMarcondes, MCCGpt_BR
unicamp.author.emailcintgoma@unicamp.brpt_BR
unicamp.authorUniv Estadual Campinas, Inst Biol, Dept Physiol & Biophys, BR-13083970 Campinas, SP, Brazil State Univ Sao Paulo, Inst Biosci, Dept Phys Educ, Sao Paulo, Brazilpt_BR
dc.subjectamino acidspt_BR
dc.subjectbody compositionpt_BR
dc.subjectleucinept_BR
dc.subjectintestinal absorptionpt_BR
dc.subjectundernourishmentpt_BR
dc.subject.wosHydroxy-beta-methylbutyratept_BR
dc.subject.wosSkeletal-musclept_BR
dc.subject.wosProtein-synthesispt_BR
dc.subject.wosAmino-acidspt_BR
dc.subject.wosGrowthpt_BR
dc.subject.wosMalnutritionpt_BR
dc.subject.wosBindingpt_BR
dc.subject.wosLiverpt_BR
dc.subject.wosRestrictionpt_BR
dc.subject.wosMethioninept_BR
dc.description.abstractOBJECTIVE: Protein malnutrition is characterized by a number of morphologic and physiologic alterations, including intestinal mucosal atrophy and impaired nutrient absorption. Impaired absorption accentuates nutritional deficiency and accelerates body weight loss and changes in body chemistry. Because leucine is a ketogenic and oxidative amino acid and stimulates the protein synthesis, we examined the ability of young rats to recover from protein malnutrition by feeding them a control balanced or a leucine-rich diet for 60 d. METHODS: At the end of the 60-d period, body, liver, and muscle weights; glucose, methionine, and leucine intestinal absorption; and carcass chemical composition were evaluated. RESULTS: Body weight gain was higher in the control balanced and leucine-rich groups than in control rats, indicating that adequate refeeding allows body weight to recover in these groups. Methionine and glucose absorptions were impaired in malnourished rats but were restored after nutritional recovery. The leucine-rich diet resulted in an increase in carcass collagen nitrogen but maintained the carcass structural nitrogen. CONCLUSIONS: These results indicated that leucine supplementation during nutritional recovery from protein malnutrition improves protein carcass restoration. However, the precise mechanism of the leucine effects involved in this response remains to be elucidated.pt
dc.relation.ispartofNutritionpt_BR
dc.relation.ispartofabbreviationNutritionpt_BR
dc.publisher.cityNew Yorkpt_BR
dc.publisher.countryEUApt_BR
dc.publisherElsevier Science Incpt_BR
dc.date.issued2004pt_BR
dc.date.monthofcirculationFEBpt_BR
dc.identifier.citationNutrition. Elsevier Science Inc, v. 20, n. 2, n. 213, n. 217, 2004.pt_BR
dc.language.isoenpt_BR
dc.description.volume20pt_BR
dc.description.issuenumber2pt_BR
dc.description.firstpage213pt_BR
dc.description.lastpage217pt_BR
dc.rightsfechadopt_BR
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policypt_BR
dc.sourceWeb of Sciencept_BR
unicamp.cruespUNESP USPpt_BR
dc.identifier.issn0899-9007pt_BR
dc.identifier.wosidWOS:000188964500010pt_BR
dc.identifier.doi10.1016/j.nut.2003.10.014pt_BR
dc.date.available2014-11-18T13:43:34Z
dc.date.available2015-11-26T16:27:51Z-
dc.date.accessioned2014-11-18T13:43:34Z
dc.date.accessioned2015-11-26T16:27:51Z-
dc.description.provenanceMade available in DSpace on 2014-11-18T13:43:34Z (GMT). No. of bitstreams: 1 WOS000188964500010.pdf: 237028 bytes, checksum: ac797dc88204134683bbf7e993a7579b (MD5) Previous issue date: 2004en
dc.description.provenanceMade available in DSpace on 2015-11-26T16:27:51Z (GMT). No. of bitstreams: 2 WOS000188964500010.pdf: 237028 bytes, checksum: ac797dc88204134683bbf7e993a7579b (MD5) WOS000188964500010.pdf.txt: 28072 bytes, checksum: fefdddc9b037175e3b5e4c2fa62d2a15 (MD5) Previous issue date: 2004en
dc.identifier.urihttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/64058pt_BR
dc.identifier.urihttp://www.repositorio.unicamp.br/handle/REPOSIP/64058
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/64058-
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