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Type: Artigo de periódico
Title: EEG features in idiopathic generalized epilepsy: Clues to diagnosis
Author: Betting, LE
Mory, SB
Lopes-Cendes, I
Li, LM
Guerreiro, MM
Guerreiro, CAM
Cendes, F
Abstract: Purpose: To investigate the EEG profile and its contribution for diagnosis and management in a group of patients with a clinical diagnosis of idiopathic generalized epilepsy (IGE) who were referred to a tertiary hospital. Methods: We retrospectively studied clinical and EEG features of 180 consecutive patients with IGE. Eighty patients were diagnosed with juvenile myoclonic epilepsy (JME), 35 had absence epilepsy (AE), 13 had generalized tonic-clonic seizures on awakening (GTCS-A), 28 had generalized tonic-clonic seizures only (TCS), and 24 had adult-onset idiopathic generalized epilepsy (AIGE). The EEGs were classified in typical (synchronous generalized spike or polyspikes-and-wave discharges with normal background), atypical (with clear focalities or asymmetries), and normal. Results: The 493 EEG exams were analyzed. The first EEG was normal in 45% of the 180 patients, and only 33% had typical abnormalities. AE had a higher proportion of typical examinations and needed fewer sequential examinations to register a typical abnormality compared with the other groups. By contrast, the serial EEG profile of TCS and AIGE showed a higher proportion of normal and atypical EEG findings. Conclusions: These findings support previous recommendations that IGE patients should be treated with appropriate therapy based on clinical history. Waiting for a typical abnormal EEG pattern can generate an unacceptable delay in the correct diagnosis and treatment of these patients. In patients with long-term epilepsy, the diagnosis may be difficult. Furthermore, serial EEGs can help to elucidate the syndromic diagnosis, especially in patients with TCS and AIGE.
Subject: idiopathic generalized epilepsy
Country: Inglaterra
Editor: Blackwell Publishing
Citation: Epilepsia. Blackwell Publishing, v. 47, n. 3, n. 523, n. 528, 2006.
Rights: fechado
Identifier DOI: 10.1111/j.1528-1167.2006.00462.x
Date Issue: 2006
Appears in Collections:Unicamp - Artigos e Outros Documentos

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