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DC Field | Value | Language |
---|---|---|
dc.contributor.CRUESP | Universidade Estadual de Campinas | pt_BR |
dc.type | Artigo de periódico | pt_BR |
dc.title | Natural polymer-based magnetic hydrogels: Potential vectors for remote-controlled drug release | pt_BR |
dc.contributor.author | Paulino, AT | pt_BR |
dc.contributor.author | Pereira, AGB | pt_BR |
dc.contributor.author | Fajardo, AR | pt_BR |
dc.contributor.author | Erickson, K | pt_BR |
dc.contributor.author | Kipper, MJ | pt_BR |
dc.contributor.author | Muniz, EC | pt_BR |
dc.contributor.author | Belfiore, LA | pt_BR |
dc.contributor.author | Tambourgi, EB | pt_BR |
unicamp.author.email | atpaulino10@gmail.com | pt_BR |
unicamp.author | Paulino, Alexandre T. Tambourgi, Elias B. Univ Estadual Campinas, Separat Proc Lab, Dept Chem Syst Engn, Sch Chem Engn, BR-13083852 Campinas, SP, Brazil | pt_BR |
unicamp.author | Paulino, Alexandre T. Erickson, Kristin Kipper, Matt J. Belfiore, Laurence A. Colorado State Univ, Dept Chem & Biol Engn, Polymer Phys & Engn Lab, Ft Collins, CO 80523 USA | pt_BR |
unicamp.author | Paulino, Alexandre T. Santa Catarina State Univ, Higher Educ Ctr W, Dept Food Engn, BR-89870000 Chapeco Pinhalzinho, SC, Brazil | pt_BR |
unicamp.author | Pereira, Antonio G. B. Fajardo, Andre R. Muniz, Edvani C. GMPC UEM, Polymer Mat & Composite Lab, Dept Chem, BR-87050900 Maringa, Parana, Brazil | pt_BR |
dc.subject | Polysaccharide | pt_BR |
dc.subject | Magnetic hydrogel | pt_BR |
dc.subject | Swelling | pt_BR |
dc.subject | Controlled release | pt_BR |
dc.subject | Curcumin | pt_BR |
dc.subject | Magnetite | pt_BR |
dc.subject.wos | Differential Scanning Calorimetry | pt_BR |
dc.subject.wos | Glycidyl Methacrylate | pt_BR |
dc.subject.wos | Chitosan | pt_BR |
dc.subject.wos | Delivery | pt_BR |
dc.subject.wos | Starch | pt_BR |
dc.subject.wos | Water | pt_BR |
dc.subject.wos | Biomaterial | pt_BR |
dc.subject.wos | Adsorption | pt_BR |
dc.subject.wos | Networks | pt_BR |
dc.subject.wos | Dextran | pt_BR |
dc.description.abstract | The preparation and characterization of natural polymer-based hydrogels that contain 50-nm diameter magnetite (i.e., FeO:Fe2O3) nanoparticles are described herein. Fourier-transform infrared spectroscopy (FTIR) analysis confirmed the efficiency of the polysaccharide-modifying process. Thermogravimetric analysis (TGA), differential scanning calorimetry (DSC), and compressive moduli demostrate that the presence of magnetite improves thermal and mechanical resistance. Transient diffusion of water in magnetic hydrogels was analyzed via boundary layer mass transfer across an expaning interface, and the degree of swelling of these polysaccharide hydrogels decreases in the presence of magnetite, with no variation in the binary diffusion mechanism. The absence of hysteresis loops and coercivity observed via magnetometry suggests that magnetic hydrogels are useful for remote-controlled drug release, as demonstrated by magnetic-field-induced release of curcumin. Experiments reveal that magnetic hydrogels with greater magnetic susceptibility have the potential to release larger concentrations of drugs from the hydrogel network. (c) 2012 Elsevier Ltd. All rights reserved. | pt |
dc.relation.ispartof | Carbohydrate Polymers | pt_BR |
dc.relation.ispartofabbreviation | Carbohydr. Polym. | pt_BR |
dc.publisher.city | Oxford | pt_BR |
dc.publisher.country | Inglaterra | pt_BR |
dc.publisher | Elsevier Sci Ltd | pt_BR |
dc.date.issued | 2012 | pt_BR |
dc.date.monthofcirculation | OCT 15 | pt_BR |
dc.identifier.citation | Carbohydrate Polymers. Elsevier Sci Ltd, v. 90, n. 3, n. 1216, n. 1225, 2012. | pt_BR |
dc.language.iso | en | pt_BR |
dc.description.volume | 90 | pt_BR |
dc.description.issuenumber | 3 | pt_BR |
dc.description.firstpage | 1216 | pt_BR |
dc.description.lastpage | 1225 | pt_BR |
dc.rights | fechado | pt_BR |
dc.rights.license | http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy | pt_BR |
dc.source | Web of Science | pt_BR |
dc.identifier.issn | 0144-8617 | pt_BR |
dc.identifier.wosid | WOS:000309091900004 | pt_BR |
dc.identifier.doi | 10.1016/j.carbpol.2012.06.051 | pt_BR |
dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | pt_BR |
dc.description.sponsorship | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) | pt_BR |
dc.description.sponsorship1 | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | pt_BR |
dc.description.sponsorship1 | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) | pt_BR |
dc.description.sponsordocumentnumber | FAPESP [2008/00285-7] | pt |
dc.description.sponsordocumentnumber | CAPES [5267/09-9] | pt |
dc.date.available | 2014-07-30T17:04:16Z | |
dc.date.available | 2015-11-26T16:45:10Z | - |
dc.date.accessioned | 2014-07-30T17:04:16Z | |
dc.date.accessioned | 2015-11-26T16:45:10Z | - |
dc.description.provenance | Made available in DSpace on 2014-07-30T17:04:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2012 | en |
dc.description.provenance | Made available in DSpace on 2015-11-26T16:45:10Z (GMT). No. of bitstreams: 2 WOS000309091900004.pdf: 1074432 bytes, checksum: fd3d0a3ed200da642530b2a2a300250a (MD5) WOS000309091900004.pdf.txt: 46116 bytes, checksum: 42c6aaa4e5a7f9db00ce24a6be27ed07 (MD5) Previous issue date: 2012 | en |
dc.identifier.uri | http://www.repositorio.unicamp.br/jspui/handle/REPOSIP/63437 | |
dc.identifier.uri | http://repositorio.unicamp.br/jspui/handle/REPOSIP/63437 | - |
Appears in Collections: | Unicamp - Artigos e Outros Documentos |
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File | Description | Size | Format | |
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WOS000309091900004.pdf | 1.05 MB | Adobe PDF | View/Open |
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