Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/63208
Type: Artigo de periódico
Title: Brainstem Involvement in Sjogren's Syndrome-Related Sensory Neuronopathy
Author: Damasceno, A
Franca, MC
Zanardi, VA
Nucci, A
Abstract: BACKGROUND AND PURPOSE Sensory neuronopathies (SN) are peripheral nervous system disorders associated with degeneration of dorsal root ganglion neurons. Magnetic resonance imaging (MRI) studies have shown abnormalities limited to T2-weighted high signal intensity in the posterior columns. METHODS AND RESULTS A 65-year-old woman with Sjogren syndrome had slowly progressive unsteadiness of gait and limb paresthesias. A blink reflex examination suggested a paramedian brainstem lesion, confirmed by MRI. CONCLUSIONS Sjogren's syndrome-related SN may be associated with a more diffuse immune-mediated aggression, involving also the brainstem, and leading to some of the blink reflex abnormalities observed in nonparaneoplastic SN.
Country: EUA
Editor: Wiley-blackwell
Rights: fechado
Identifier DOI: 10.1111/j.1552-6569.2009.00393.x
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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