Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/631
Type: Artigo de periódico
Title: Undifferentiated Spondyloarthritis: A Longterm Followup
Author: SAMPAIO-BARROS, Percival D.
BORTOLUZZO, Adriana B.
CONDE, Roseneide A.
COSTALLAT, Lilian Tereza L.
SAMARA, Adil M.
BERTOLO, Manoel B.
Abstract: Objective. To analyze the longterm followup of a series of Brazilian patients with undifferentiated spondyloarthritis (uSpA). Methods. Prospective study analyzing a group of 111 patients with the diagnosis of uSpA, fulfilling the European Spondylarthropathy Study Group and the Amor criteria, who were followed for 5 to 10 years in a single university referral center. Patients had their outcome analyzed at 5, 7, and 10 years. Results. There was a predominance of men (81.1%), white ethnicity (78.4%), and positive HLA-B27 (61.3%), with a mean age at onset of 27.2 years. Twenty-seven patients presented development to ankylosing spondylitis (AS; 24.3%) and 3 to psoriatic arthritis (PsA; 2.7%), while 25 patients (22.5%) went into remission during the followup. Univariate logistic regression analysis revealed that ethnicity, HLA-B27, buttock pain, inflammatory low back pain, ankle involvement, grade I sacroiliitis at the beginning of the study, and the use of sulfasalazine were statistically associated with progression to AS. Multivariate logistic regression analysis revealed that HLA-B27 (p = 0.035, OR 6.720.95% CI 11.45-39.43) and buttock pain (p = 0.009, OR 6.211, 95% CI 1.591-24.25) were statistically associated with progression to AS. Conclusion. In a longterm followup of 111 Brazilian patients with uSpA, HLA-B27 and buttock pain were significant predictors of progression to a definite disease. (First Release May 1 2010; J Rheumatol 2010;37:1195-9; doi:10.3899/jrheum.090625)
Subject: UNDIFFERENTIATED SPONDYLOARTHRITHIS
OUTCOME
HLA-B27
SACROILIITIS
Country: Canadá
Editor: J RHEUMATOL PUBL CO
Citation: JOURNAL OF RHEUMATOLOGY, v.37, n.6, p.1195-1199, 2010
Rights: fechado
Identifier DOI: 10.3899/jrheum.090625
Address: http://dx.doi.org/10.3899/jrheum.090625
http://apps.isiknowledge.com/InboundService.do?Func=Frame&product=WOS&action=retrieve&SrcApp=EndNote&UT=000279194600019&Init=Yes&SrcAuth=ResearchSoft&mode=FullRecord
Date Issue: 2010
Appears in Collections:FCM - Artigos e Materiais de Revistas Científicas

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