Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/63085
Type: Artigo de periódico
Title: CHEMOTHERAPEUTIC TREATMENTS INVOLVING DRUG-RESISTANCE AND LEVEL OF NORMAL-CELLS AS A CRITERION OF TOXICITY
Author: COSTA, MIS
BOLDRINI, JL
BASSANEZI, RC
Abstract: A system of differential equations for the control of tumor cells growth in a cycle nonspecific chemotherapy is presented. Drug resistance and toxicity conveyed through the level of normal cells are taken into account in a class of optimal control problems. Alternative treatments for the exponential tumor growth are set forth for cases where optimal treatments are not available.
Editor: Elsevier Science Publ Co Inc
Rights: fechado
Identifier DOI: 10.1016/0025-5564(94)00028-X
Date Issue: 1995
Appears in Collections:Unicamp - Artigos e Outros Documentos

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