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dc.contributor.CRUESPUniversidade Estadual de Campinaspt_BR
dc.typeArtigo de periódicopt_BR
dc.titleChemical and technological evaluation of the Phyllanthus niruri aerial parts as a function of cultivation and harvesting conditionspt_BR
dc.contributor.authorCouto, AGpt_BR
dc.contributor.authorKunzler, MLpt_BR
dc.contributor.authorSpaniol, Bpt_BR
dc.contributor.authorMagalhaes, PMpt_BR
dc.contributor.authorOrtega, GGpt_BR
dc.contributor.authorPetrovick, PRpt_BR
unicamp.authorCouto, Angelica G. Univ Vale Itajai, Programa Posgrad Ciencias Farmaceut, BR-88302202 Itajai, SC, Brazilpt_BR
unicamp.authorKunzler, Marli L. Univ Fed Rio Grande do Sul, Fac Farm, BR-90046900 Porto Alegre, RS, Brazilpt_BR
unicamp.authorSpaniol, Barbara Univ Feevale, Curso Farm, Novo Hamburgo, Brazilpt_BR
unicamp.authorMagalhaes, Pedro M. Univ Estadual Campinas, Ctr Pluridisciplinar Pesquisas Quim Biol & Agr, Div Agrotecnol, Campinas, Brazilpt_BR
unicamp.authorOrtega, George G. Petrovick, Pedro R. Univ Fed Rio Grande do Sul, Fac Farm, Programa Posgrad Ciencias Farmaceut, BR-90046900 Porto Alegre, RS, Brazilpt_BR
dc.subjectgallic acidpt_BR
dc.subjectherbal drugpt_BR
dc.subjectPhyllanthus niruript_BR
dc.description.abstractTea from Phyllanthus niruri L., Phyllanthaceae, aerial parts is commonly used by Brazilian folk medicine for its benefits on the treatment of genitourinary disorders, for what the polyphenolic compounds are mainly responsible. The yield of such compounds may be influenced by several variables related with the plant growth. The effects of planting periods and harvesting conditions are investigated in this work, including four different seasons. The cultivation was characterized by dry mass yield of aerial parts, and the effect of pruning was analyzed. Leaves, stems and their mixtures were analyzed after drying and milling. Loss on drying and water soluble extractives were used as physical parameters for quality control. Flavonoid content and gallic acid were chosen as chemical markers for this work. The spectrophotometric trial based on the aluminum chloride complexes was applied to evaluate the total flavonoids content. Gallic acid contents were measured from the water extractive solutions by high-performance liquid chromatography. The pruning caused a positive influence on the amount of leaves and stems. The highest flavonoids and gallic acid contents were found in the leaves, which were developed over the summer and the winter, respectively, both from the second harvesting (after pruning). Chomatographic profile by HPLC was characterizes by the presence of gallic acid and two other major peaks (not identified substances), which relation was peculiar to each aerial part. In conclusion, these results suggest that even under less favorable climatic conditions, in winter, the pruning seems to cause a strong influence over the P. niruri polyphenolics production. Indeed, the total flavonoids content, as well as the HPLC profile, can be used as indicative parameters of the ratio of leaves and stem in the vegetal raw
dc.relation.ispartofRevista Brasileira De Farmacognosia-brazilian Journal Of Pharmacognosypt_BR
dc.relation.ispartofabbreviationRev. Bras. Farmacogn.-Braz. J. Pharmacogn.pt_BR
dc.publisher.cityJoao Pessoapt_BR
dc.publisherSoc Brasileira Farmacognosiapt_BR
dc.identifier.citationRevista Brasileira De Farmacognosia-brazilian Journal Of Pharmacognosy. Soc Brasileira Farmacognosia, v. 23, n. 1, n. 36, n. 43, 2013.pt_BR
dc.sourceWeb of Sciencept_BR
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)pt_BR
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)pt_BR
dc.description.sponsorship1Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)pt_BR
dc.description.sponsorship1Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)pt_BR
dc.description.provenanceMade available in DSpace on 2014-07-30T16:52:14Z (GMT). No. of bitstreams: 0 Previous issue date: 2013en
dc.description.provenanceMade available in DSpace on 2015-11-26T16:38:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2013en
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