Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/62466
Type: Artigo de periódico
Title: Dorzolamide x Apraclonidine in the prevention of the intraocular pressure spike after Nd : YAG laser posterior capsulotomy
Author: Arieta, CEL
Amaral, MS
Matuda, E
Crosta, C
Moreira, DD
Jose, NK
Abstract: Objective. To evaluate the efficacy of dorzolamide compared to apraclonidine, in the prevention of the intra-ocular pressure (IOP) spike after Nd: YAG laser posterior capsulotomy. Site. Department of Ophthalmology, State University of Campinas (UNICAMP) General Hospital, Campinas, Sao Paulo, Brazil. Methods. In a double masked prospective clinical trial, 217 eyes from 217 patients were randomly assigned to receive either dorzolamide 2 h before and placebo 1 h before Nd: YAG laser capsulotomy or placebo 2 h before and apraclonidine 1 h before the procedure. Inclusion criteria were secondary cataracts with reduction in best corrected visual acuity (BCVA < 20/40), absence of manifest or suspected glaucoma and no known hypersensitivity to the study drugs. IOP was measured 2 h and 1 h before applying the laser, and 1 h, 2 h, 3 h and 7 days after. Results. There were no statistically significant differences between the two groups regarding the IOP 2 h and 1 h before the procedure, and 1 h, 2 h, 3 h and 7 days after the laser treatment (p values, respectively: 0.077, 0.21, 0.085, 0.36, and 0.60). Conclusion. The results of this study suggest that dorzolamide is as safe and effective as apraclonidine in the prevention of the IOP elevation after Nd: YAG laser posterior capsulotomy. Synopsis. The efficacy of dorzolamide was compared to apraclonidine in the prevention of the intraocular pressure spike after Nd: YAG laser posterior capsulotomy in 217 patients and the results were similar with both drugs.
Country: Holanda
Editor: Swets Zeitlinger Publishers
Rights: fechado
Identifier DOI: 10.1076/ceyr.25.4.237.13484
Date Issue: 2002
Appears in Collections:Unicamp - Artigos e Outros Documentos

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