Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/62267
Type: Artigo de periódico
Title: Nutritional recovery with a soybean flour diet improves the insulin response to a glucose load without modifying glucose homeostasis
Author: Oliveira, EDA
Cheim, LMG
Veloso, RV
Arantes, VC
Reis, MADB
Carneiro, EM
Boschero, AC
Latorraca, MQ
Abstract: Objective: We investigated the effect of nutritional recovery with a soybean flour diet on glucose tolerance, insulin response to a glucose load, and the action of insulin in adult rats exposed to a protein deficiency during intrauterine life and lactation. Methods: Male Wistar rats from dams fed a normal- or low-protein diet during pregnancy and lactation were maintained after weaning by feeding them normal-protein isoenergetic diets containing soybean flour or casein and low-protein casein diet. Results: Rats fed a soybean flour diet had a lower final body weight, epididymal fat pad, carcass fat content, and liver glycogen level. The serum glucose concentrations in the basal and fed states and the area under the glucose curves during the glucose tolerance test were not significantly different among the four groups. Their serum insulin levels during fasting were observed to be similar to those fed a casein diet. These rats also had a higher serum insulin levels in a fed state and total area under the insulin curves in response to a glucose load, but a lower ratio of area under the glucose/insulin curves during the glucose tolerance test than those fed a casein diet. Conclusion: These results indicate that nutritional recovery with a soybean flour diet improved the insulin response to a glucose load and decreased the sensitivity to insulin, at least in hepatic tissue. (C) 2008 Elsevier Inc. All rights reserved.
Subject: soybean diet
serum insulin
glucose tolerances
nutritional recovery
rats
Country: EUA
Editor: Elsevier Science Inc
Rights: fechado
Identifier DOI: 10.1016/j.nut.2007.09.002
Date Issue: 2008
Appears in Collections:Unicamp - Artigos e Outros Documentos

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