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dc.contributor.CRUESPUniversidade Estadual de Campinaspt_BR
dc.typeArtigo de periódicopt_BR
dc.titleNuclear alterations of cells and atypical metaplastic cells in cervical smears are predictive criteria of high-grade cervical intraepithelial neoplasiapt_BR
dc.contributor.authorDufloth, RMpt_BR
dc.contributor.authorMessias-Silva, SMpt_BR
dc.contributor.authorAndrade, LApt_BR
dc.contributor.authordi Loreto, Cpt_BR
dc.contributor.authorMunhoz, DMpt_BR
dc.contributor.authorZeferino, LCpt_BR
unicamp.authorUNICAMP, CAISM, Integrated Healthcare Ctr Women, Campinas, SP, Brazil UNICAMP, Sch Med Sci, Campinas, SP, Brazil Adolfo Lutz Inst, Sao Paulo Hlth Dept, Sao Paulo, Brazilpt_BR
dc.subjectcervical smearpt_BR
dc.subjectmetaplastic cellspt_BR
dc.subjectpredictive valuept_BR
dc.subjectscreeningpt_BR
dc.subjectcervical cancerpt_BR
dc.subject.wosPapanicolaou Smearspt_BR
dc.subject.wosUndetermined Significancept_BR
dc.subject.wosSquamous-cellspt_BR
dc.subject.wosAbnormal-cellspt_BR
dc.subject.wosCytologypt_BR
dc.subject.wosLesionspt_BR
dc.subject.wosAscuspt_BR
dc.subject.wosReproducibilitypt_BR
dc.subject.wosProgressionpt_BR
dc.subject.wosFeaturespt_BR
dc.description.abstractDiagnoses based on the screening of cervical smears show low interobserver reproducibility and are frequently discordant with the final histological diagnosis. The aim of this study was to identify which of the cytomorphologic criteria used in the screening of cervical smears were most predictive of the histopathological grades of cervical intraepithelial neoplasia. The abnormal cervical smears of 206 women were reviewed blindly according to 22 pre-established cytomorphological criteria. Colposcopic evaluation was carried out in all cases. The marked presence of several nuclear criteria frequently found together in the same smear was associated with high grade intraepithelial neoplasia regardless of the presence of any other criteria. On the other hand, when the nuclear criteria were less evident, the cluster of criteria related to metaplastic cells was predictive of a diagnosis of high-grade intraepithelial neoplasia. Focusing on selected cytological criteria can aggregate predictive value to cervical smear diagnoses.pt
dc.relation.ispartofEuropean Journal Of Gynaecological Oncologypt_BR
dc.relation.ispartofabbreviationEur. J. Gynaecol. Oncol.pt_BR
dc.publisher.cityMontrealpt_BR
dc.publisher.countryCanadápt_BR
dc.publisherI R O G Canada, Incpt_BR
dc.date.issued2005pt_BR
dc.identifier.citationEuropean Journal Of Gynaecological Oncology. I R O G Canada, Inc, v. 26, n. 2, n. 186, n. 190, 2005.pt_BR
dc.language.isoenpt_BR
dc.description.volume26pt_BR
dc.description.issuenumber2pt_BR
dc.description.firstpage186pt_BR
dc.description.lastpage190pt_BR
dc.rightsfechadopt_BR
dc.sourceWeb of Sciencept_BR
dc.identifier.issn0392-2936pt_BR
dc.identifier.wosidWOS:000228533500012pt_BR
dc.date.available2014-07-30T14:48:49Z
dc.date.available2015-11-26T16:45:39Z-
dc.date.accessioned2014-07-30T14:48:49Z
dc.date.accessioned2015-11-26T16:45:39Z-
dc.description.provenanceMade available in DSpace on 2014-07-30T14:48:49Z (GMT). No. of bitstreams: 0 Previous issue date: 2005en
dc.description.provenanceMade available in DSpace on 2015-11-26T16:45:39Z (GMT). No. of bitstreams: 0 Previous issue date: 2005en
dc.identifier.urihttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/62177
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/62177-
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