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Type: Artigo de periódico
Title: Noninvasive Ventilation in a Pregnant Patient With Respiratory Failure From All-Trans-Retinoic-Acid (ATRA) Syndrome
Author: Bassani, MA
de Oliveira, ABF
Neto, AFO
Abstract: We saw a 34-year-old pregnant woman with acute promyelocytic leukemia, who developed acute respiratory failure from all-trans-retinoic acid (ATRA) syndrome. We applied noninvasive ventilation (NIV, continuous positive airway pressure plus pressure-support ventilation) to try to improve gas exchange, reduce the work of breathing, and prevent intubation. Initially we applied NIV continuously (24 hours a day), then gradually reduced the daily amount of time on NIV as her condition improved. She was discharged from the intensive care unit after 12 days. Three months after hospital discharge she gave vaginal birth to a healthy female baby. NIV was effective and safe for the mother and fetus, and NIV should be considered for respiratory failure in pregnant patients, especially if immunosuppressed.
Subject: pregnancy
promyelocytic leukemia
all-trans-retinoic acid syndrome
noninvasive ventilation
acute respiratory failure
mechanical ventilation
Country: EUA
Editor: Daedalus Enterprises Inc
Rights: fechado
Identifier DOI: 10.4187/002013209793800466
Date Issue: 2009
Appears in Collections:Unicamp - Artigos e Outros Documentos

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