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dc.contributor.CRUESPUniversidade Estadual de Campinaspt_BR
dc.typeArtigo de periódicopt_BR
dc.titleNoninvasive ventilation acutely modifies heart rate variability in chronic obstructive pulmonary disease patientspt_BR
dc.contributor.authorBorghi-Silva, Apt_BR
dc.contributor.authorReis, MSpt_BR
dc.contributor.authorMendes, RGpt_BR
dc.contributor.authorPantoni, CBFpt_BR
dc.contributor.authorSimoes, RPpt_BR
dc.contributor.authorMartins, LEBpt_BR
dc.contributor.authorCatai, AMpt_BR
unicamp.authorBorghi-Silva, Audrey Reis, Michel Silva Mendes, Renata Gonqalves Falasco Pantoni, Camila Bianca Simoes, Rodrigo Polaquini Catai, Aparecida Maria Univ Fed Sao Carlos, Cardiopulm Physiotherapy Lab, Dept Physiotherapy, BR-13565905 Sao Carlos, SP, Brazilpt_BR
unicamp.authorBarreto Martins, Luis Eduardo Univ Estadual Campinas, Exercise Physiol Lab, Fac Phys Educ, Campinas, SP, Brazilpt_BR
dc.subjectchronic obstructive pulmonary diseasept_BR
dc.subjectbi-level positive airway pressurept_BR
dc.subjectheart rate variabilitypt_BR
dc.subject.wosPositive Airway Pressurept_BR
dc.subject.wosAcute Respiratory-failurept_BR
dc.subject.wosSpontaneous Baroreflexpt_BR
dc.description.abstractObjective: The purpose of present study was to evaluate the acute effects of bi-level positive airway pressure (BiPAP) on heart rate variability (HRV) of stable chronic obstructive pulmonary disease patients (COPD). Methods: Nineteen mates with COPD (69 +/- 8 years and with forced expiratory volume in 1 s <50% of predicted) and eight healthy sedentary age-matched (69 years) males in the control group (CG) were evaluated during two conditions of controlled respiratory rate: spontaneous breathing (SB) and BiPAP (inspiratory and expiratory levels between 12-14 cmH(2)O and 4-6 cmH(2)O, respectively). Peripheral oxygen saturation (SpO(2)), end-tidal of carbon dioxide (ETCO2), systolic blood pressure (SBP) and R-R interval were obtained. HRV was analyzed by time (RMSSD and SDNN index) and frequency domains (high frequency - HF, low frequency - LF and HF/LF ratio). Results: Significant reduction of ETCO2 and SBP in both groups and increase of SpO(2) in COPD group was observed during BiPAP ventilation (p < 0.05). During spontaneous breathing, patients with COPD presented lower values of LF, LF/HF and higher values of HF when compared to CG (p < 0.05). However, HF was significantly reduced and LF increased during BiPAP ventilation (58 +/- 19-48 +/- 15 and 41 +/- 19-52 +/- 15un, respectively) in COPD group. Significant correlations between delta BiPAP-SB (Delta) ETCO2 and Delta HF were found (r = 0.89).pt
dc.relation.ispartofRespiratory Medicinept_BR
dc.relation.ispartofabbreviationRespir. Med.pt_BR
dc.publisherW B Saunders Co Ltdpt_BR
dc.identifier.citationRespiratory Medicine. W B Saunders Co Ltd, v. 102, n. 8, n. 1117, n. 1123, 2008.pt_BR
dc.sourceWeb of Sciencept_BR
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.description.sponsorship1Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.description.sponsordocumentnumberFAPESP [05/59427-7]pt
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