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dc.contributor.CRUESPUniversidade Estadual de Campinaspt_BR
dc.typeArtigo de periódicopt_BR
dc.titleDetermination of the allele frequencies of three polymorphisms in the promoter region of the human protein C gene in three Brazilian ethnic groupspt_BR
dc.contributor.authorMendes, CPOpt_BR
dc.contributor.authorHackel, Cpt_BR
dc.contributor.authorArruda, VRpt_BR
dc.contributor.authorAnnichino-Bizzacchi, JMpt_BR
unicamp.author.emailjoyce@obelix.unicamp.brpt_BR
unicamp.authorUniv Estadual Campinas, Hematol Hematherapy Ctr, Dept Clin Med, BR-13081970 Campinas, SP, Brazil Univ Estadual Campinas, Dept Med Genet, BR-13081970 Campinas, SP, Brazilpt_BR
dc.subjectprotein Cpt_BR
dc.subjectpromoterpt_BR
dc.subjectpolymorphismspt_BR
dc.subject.wosIndianspt_BR
dc.description.abstractThe frequencies of three polymorphisms in the promoter region of the human protein C gene have been determined in th ree ethnic groups of the Brazilian population, The allele frequencies observed in south-eastern Brazilian Caucasians and Blacks were similar to the values obtained for the Dutch population and were different from those observed in Amazonian Indians living in the north of the country, The most frequent genotypic combination found in this latter group was the CC/GG/<(AA)under bar> genotype, which is very rare among Caucasians, The complete heterozygous genotype CT/AG/<(AT)under bar> was the most frequent both in Brazilian Caucasians and Blacks, Among 27 possible genotypic combinations, 21 were found in the Caucasian group and 15 in Blacks, revealing a high degree of genetic diversity in south-eastern Brazilian populations.pt
dc.relation.ispartofHuman Hereditypt_BR
dc.relation.ispartofabbreviationHum. Hered.pt_BR
dc.publisher.cityBaselpt_BR
dc.publisher.countrySuíçapt_BR
dc.publisherKargerpt_BR
dc.date.issued1999pt_BR
dc.identifier.citationHuman Heredity. Karger, v. 49, n. 1, n. 27, n. 30, 1999.pt_BR
dc.language.isoenpt_BR
dc.description.volume49pt_BR
dc.description.issuenumber1pt_BR
dc.description.firstpage27pt_BR
dc.description.lastpage30pt_BR
dc.rightsfechadopt_BR
dc.rights.licensehttp://www.karger.com/Services/RightsPermissionspt_BR
dc.sourceWeb of Sciencept_BR
dc.identifier.issn0001-5652pt_BR
dc.identifier.wosidWOS:000078313300006pt_BR
dc.identifier.doi10.1159/000022836pt_BR
dc.date.available2014-12-02T16:26:52Z
dc.date.available2015-11-26T16:33:20Z-
dc.date.accessioned2014-12-02T16:26:52Z
dc.date.accessioned2015-11-26T16:33:20Z-
dc.description.provenanceMade available in DSpace on 2014-12-02T16:26:52Z (GMT). No. of bitstreams: 1 WOS000078313300006.pdf: 296297 bytes, checksum: cd36daf80d9546ff95093b6714906175 (MD5) Previous issue date: 1999en
dc.description.provenanceMade available in DSpace on 2015-11-26T16:33:20Z (GMT). No. of bitstreams: 2 WOS000078313300006.pdf: 296297 bytes, checksum: cd36daf80d9546ff95093b6714906175 (MD5) WOS000078313300006.pdf.txt: 17221 bytes, checksum: b16696445810cb386bf90bcdfafa83dd (MD5) Previous issue date: 1999en
dc.identifier.urihttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/61436pt_BR
dc.identifier.urihttp://www.repositorio.unicamp.br/handle/REPOSIP/61436
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/61436-
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