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Type: Artigo de periódico
Title: Determinants of serum lipoprotein(a) concentration in normolipidaemic individuals without clincal atherosclerosis
Author: Dalpino, F
Sodre, FL
Castilho, LN
de Faria, EC
Abstract: Background: Lipoprotein(a) (Lp(a)) is an independent risk factor for coronary artery diseases. The main objective of this work was to evaluate the determinants of plasma Lp(a) concentrations in normolipidaemic individuals. Methods: Immunonephelometric quantification of Lp(a) was made in 177 volunteers. A multivariate analysis was employed to verify the influence of clinical and biochemical parameters on plasma Lp(a) concentration. Results: The serum Lp(a) concentration in this population ranged from 0.7 to 40 nmol/L. The Lp(a) predictors were: sex (female), HDL2 triglyceride (negative) and LDL-cholesterol (positive). Conclusions: The modulation of plasma Lp(a) concentration in this study points to pro-atherogenic lipoprotein associations.
Country: Inglaterra
Editor: Royal Soc Medicine Press Ltd
Rights: fechado
Identifier DOI: 10.1258/0004563054889918
Date Issue: 2005
Appears in Collections:Unicamp - Artigos e Outros Documentos

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