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|Type:||Artigo de periódico|
|Title:||Lack of Arg972 polymorphism in the IRS1 gene in Parakand Brazilian Indians|
|Abstract:||Several polymorphisms in the insulin receptor substrate-1 (IRS1) gene have been reported in the last years. The most common IRS1 variant, a Gly --> Arg substitution at codon 972 (Arg972 IRS1), is more prevalent among subjects who have features of insulin resistance syndrome associated, or not, with type 2 diabetes in European populations. To determine whether the absence of IRS1 polymorphism is a more general characteristic of Paleo-Indian-derived populations, we examined the Arg972 IRS1 polymorphism in Parakana Indians and found a lack of this polymorphism in the Parakana population.|
|Subject:||IRSI (insulin receptor substrate-1 gene)|
|Editor:||Wayne State Univ Press|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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