Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/61009
Type: Artigo de periódico
Title: Kinetics of Monofluorophosphate Hydrolysis in a Bacterial Test Plaque in situ
Author: Tenuta, LMA
Cury, AAD
Tabchoury, CPM
Moi, GP
Silva, WJ
Cury, JA
Abstract: Models to evaluate the anticaries potential of fluoride (F) formulations containing monofluorophosphate (MFP) should consider the release of F ion to the oral environment by its enzymatic hydrolysis. This was tested in situ, using a test plaque of a strain of Streptococcus mutans which presents high MFPase activity at pH 5.0. The test plaque was exposed to non-F or MFP (1,450 mu g F/g) dentifrices and the fluid phase of the plaque was analyzed after 15, 30, 45 and 75 min. MFP concentration in the plaque fluid decreased over time after exposure to MFP dentifrice, but F ion reached 134.9 +/- 32.0 mu M at 15 min and decreased significantly only at 75 min, suggesting continuous MFP hydrolysis by the test plaque. Copyright (C) 2010 S. Karger AG, Basel
Subject: Dentifrice
Fluoride
Monofluorophosphate
Plaque
Phosphatase
Country: Suíça
Editor: Karger
Rights: fechado
Identifier DOI: 10.1159/000279466
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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