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| Type: | Artigo de periódico |
| Title: | Isolation of protein factors from opossum (Didelphis albiventris) serum which protect against Bothrops jararaca venom |
| Author: | Farah, MDL One, M Novello, JC Toyama, MH Perales, J Moussatche, H Domont, GB Oliveira, B Marangoni, S |
| Abstract: | The fractionation of Didelphis albiventris serum by DEAE-Sephadex A50 yields a fraction (DA2) which protects the opossum against Bothrops venom. One polypeptide (DA2-II) responsible for this protection was isolated from fraction DA2 by ion exchange chromatography and biochemically characterized. DA2-II is a 43,000 mol. wt glycoprotein with the following N-terminal sequence: LKAMDTTPPLKIKKEPVK. Pairwise comparison of the amino acid sequence with four anti-hemorrhagic factors isolated from other opossum species indicated that DA2-II possesses high similarity (60-80%) with these proteins. Copyright (C) 1996 Elsevier Science Ltd |
| Country: | Inglaterra |
| Editor: | Pergamon-elsevier Science Ltd |
| Citation: | Toxicon. Pergamon-elsevier Science Ltd, v. 34, n. 9, n. 1067, n. 1071, 1996. |
| Rights: | fechado |
| Date Issue: | 1996 |
| Appears in Collections: | Unicamp - Artigos e Outros Documentos |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| WOSA1996VL39000013.pdf | 381.35 kB | Adobe PDF | View/Open |
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