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Type: Artigo de periódico
Title: Isolation of protein factors from opossum (Didelphis albiventris) serum which protect against Bothrops jararaca venom
Author: Farah, MDL
One, M
Novello, JC
Toyama, MH
Perales, J
Moussatche, H
Domont, GB
Oliveira, B
Marangoni, S
Abstract: The fractionation of Didelphis albiventris serum by DEAE-Sephadex A50 yields a fraction (DA2) which protects the opossum against Bothrops venom. One polypeptide (DA2-II) responsible for this protection was isolated from fraction DA2 by ion exchange chromatography and biochemically characterized. DA2-II is a 43,000 mol. wt glycoprotein with the following N-terminal sequence: LKAMDTTPPLKIKKEPVK. Pairwise comparison of the amino acid sequence with four anti-hemorrhagic factors isolated from other opossum species indicated that DA2-II possesses high similarity (60-80%) with these proteins. Copyright (C) 1996 Elsevier Science Ltd
Country: Inglaterra
Editor: Pergamon-elsevier Science Ltd
Citation: Toxicon. Pergamon-elsevier Science Ltd, v. 34, n. 9, n. 1067, n. 1071, 1996.
Rights: fechado
Date Issue: 1996
Appears in Collections:Unicamp - Artigos e Outros Documentos

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