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|Type:||Artigo de periódico|
|Title:||Iodine-Catalyzed Aza-Prins Cyclization: Metal-Free Synthesis and Antiproliferative Activity of Hexahydrobenzo[f]isoquinolines|
de Carvalho, JE
|Abstract:||A series of hexahydrobenzo[f]isoquinolines were synthesized by an iodine-catalyzed aza-Prins cyclization under metal-free conditions. An aliphatic or an aromatic aldehyde can be used as the carbonyl component in this reaction, which can also be performed efficiently under solvent-free conditions. During this study, we discovered new compounds with moderate antitumor activities.|
|Editor:||Georg Thieme Verlag Kg|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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