Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/60313
Type: Artigo de periódico
Title: Intake of jaboticaba peel attenuates oxidative stress in tissues and reduces circulating saturated lipids of rats with high-fat diet-induced obesity
Author: Batista, AG
Lenquiste, SA
Cazarin, CBB
da Silva, JK
Luiz-Ferreira, A
Bogusz, S
Hantao, LW
de Souza, RN
Augusto, F
Prado, MA
Marostica, MR
Abstract: The bioactive compounds of freeze-dried jaboticaba peel (FJP), serum lipids and the antioxidant status of rats fed high-fat diets containing different doses of FJP were evaluated. Obesity was induced and three groups of the obese animals received high-fat diet with 1%, 2% and 4% FJP added (J1, J2 and J4, respectively). The HPLC-DAD analyses of the polyphenols in the FJP showed four compounds: gallic acid, cyanidin 3-glucoside, ellagic acid, and quercetin. The serum saturated fatty acids were reduced in J1 and J4-fed animals. The antioxidant defenses of plasma were increased in the J2 and J4-fed animals. All the FJP diets prevented lipid peroxidation in the liver and increased its antioxidant defenses. Lipid peroxidation in brain decreased with an increasing FJP content in the diet. The antioxidant status of the kidneys of J2 and J4-fed animals increased. Thus, FJP could be an alternative to minimize the high-fat diet-induced oxidative stress and circulating saturated lipids. (C) 2013 Elsevier Ltd. All rights reserved.
Subject: Myrciaria jaboticaba (Vell.) Berg.
Obesity
Polyphenols
Antioxidant defenses
Lipid peroxidation
Fatty acids methyl esters
Country: Holanda
Editor: Elsevier Science Bv
Rights: fechado
Identifier DOI: 10.1016/j.jff.2013.11.011
Date Issue: 2014
Appears in Collections:Unicamp - Artigos e Outros Documentos

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