Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/59917
Type: Artigo de periódico
Title: PLASMID CODING FOR DRUG-RESISTANCE AND INVASION OF EPITHELIAL-CELLS IN ENTEROPATHOGENIC ESCHERICHIA-COLI-0111-H-
Author: SCALETSKY, ICA
GATTI, MSV
DASILVEIRA, JF
DELUCA, IMS
FREYMULLER, E
TRAVASSOS, LR
Abstract: Enteropathogenic Escherichia coli (EPEC) can adhere to, invade and multiply in human epithelial cells. To define the elements required for bacterial invasion, we isolated from an 0111:H- EPEC a 6.6 kb plasmid that is capable of conferring to an avirulent, non-adherent E. coli K12 strain (DK1) the capacity to invade epithelial cells. With this system a dissociation was possible between bacterial invasion and adherence to epithelial cells. Bacteria containing this plasmid synthesise a protein of 32 kDa (pi 4.93) which seemed to be required for cell invasion. The results provide a new basis for strategies to prevent EPEC infections.
Subject: EPEC
INVASION
PLASMID
Country: Inglaterra
Editor: Academic Press (london) Ltd
Rights: fechado
Identifier DOI: 10.1006/mpat.1995.0035
Date Issue: 1995
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
WOSA1995RV31200002.pdf2.56 MBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.