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|Type:||Artigo de periódico|
|Title:||Continuous positive airway pressure increases inspiratory capacity of COPD patients|
|Author:||SOARES, Silvia M. T. P.|
OLIVEIRA, Rosmari A. R. A.
FRANCA, Suelene A.
REZENDE, Silvio M.
KACMAREK, Robert M.
CARVALHO, Carlos R. R.
|Abstract:||Background and objective: Hyperinflation with a decrease in inspiratory capacity (IC) is a common presentation for both unstable and stable COPD patients. As CPAP can reduce inspiratory load, possibly secondary to a reduction in hyperinflation, this study examined whether CPAP would increase IC in stable COPD patients. Methods: Twenty-one stable COPD patients (nine emphysema, 12 chronic bronchitis) received a trial of CPAP for 5 min at 4, 7 and 11 cmH(2)O. Fast and slow VC (SVC) were measured before and after each CPAP trial. In patients in whom all three CPAP levels resulted in a decreased IC, an additional trial of CPAP at 2 cmH(2)O was conducted. For each patient, a `best CPAP` level was defined as the one associated with the greatest IC. This pressure was then applied for an additional 10 min followed by spirometry. Results: Following application of the `best CPAP`, the IC and SVC increased in 15 patients (nine emphysema, six chronic bronchitis). The mean change in IC was 159 mL (95% CI: 80-237 mL) and the mean change in SVC was 240 mL (95% CI: 97-386 mL). Among these patients, those with emphysema demonstrated a mean increase in IC of 216 mL (95% CI: 94-337 mL). Six patients (all with chronic bronchitis) did not demonstrate any improvement in IC. Conclusions: The best individualized CPAP can increase inspiratory capacity in patients with stable COPD, especially in those with emphysema.|
non-invasive mechanical ventilation
|Citation:||RESPIROLOGY, v.13, n.3, p.387-393, 2008|
|Appears in Collections:||HC - Artigos e Outros Documentos|
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