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Type: Artigo de periódico
Title: Asbestos-related Disease Progression of Parenchymal Abnormalities on High-resolution CT
Author: SILVA, C. Isabela S.
MUELLER, Nestor L.
NEDER, J. Alberto
NOGUEIRA, Cristiano Rabelo
NAPOLIS, Lara Maris
BAGATIN, Ericson
NERY, Luiz E.
Abstract: Purpose: To evaluate the changes over time in the pattern and extent of parenchymal abnormalities in asbestos-exposed workers after cessation of exposure and to compare 3 proposed semiquantitative methods with a careful side-by-side comparison of the initial and the follow-Lip computed tomography (CT) images. Materials and Methods: The study included 52 male asbestos workers (mean age SD, 62.2y +/- 8.2) who had baseline high-resolution CT after cessation of exposure and follow-up CT 3 to 5 years later. Two independent thoracic radiologists quantified the findings according to the scoring systems proposed by Huuskonen, Gamsu, and Sette and then did a side-by-side comparison of the 2 sets of scans without awareness of the dates of the CT scans. Results: There was no difference in the prevalence of the 2 most common parenchymal abnormalities (centrilobular small dotlike or branching opacities and interstitial lines) between the initial and follow-up CT scans. Honeycombing (20%) and traction bronchiectasis and bronchiolectasis (50%) were seen more commonly on the follow-up CT than on the initial examination (10% and 33%, respectively) (P = 0.01). Increased extent of parenchymal abnormalities was evident on side-by-side comparison in 42 (81%) patients but resulted in an increase in score in at least 1 semiquantitative system in only 16 (31%) patients (all P > 0.01, signed test). Conclusions: The majority of patients with previous asbestos exposure show evidence of progression of disease on CT at 3 to 5 years follow-up but this progression is usually not detected by the 3 proposed semiquantitative scoring schemes.
Subject: asbestos
computed tomography
pleural plaques
Country: Estados Unidos
Citation: JOURNAL OF THORACIC IMAGING, v.23, n.4, p.251-257, 2008
Rights: fechado
Identifier DOI: 10.1097/RTI.0b013e31817e352a
Date Issue: 2008
Appears in Collections:FCM - Artigos e Outros Documentos

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