Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/59397
Type: Artigo de periódico
Title: PHARMACOKINETIC PROFILE OF 2 DIFFERENT PHARMACEUTICAL FORMS OF THEOPHYLLINE (A SLOW-RELEASE TABLET AND A SYRUP) AFTER MULTIPLE-DOSE ADMINISTRATION TO HEALTHY-HUMAN VOLUNTEERS
Author: MUSCARA, MN
HOFSTATTER, EA
DENUCCI, G
Abstract: Due to the narrow therapeutic range of theophylline, plasma concentrations of this drug are monitored in patients undergoing chronic therapy. Slow-release preparations avoid the fluctuations in plasma levels and improve patient compliance. In this study, we have compared the pharmacokinetic profiles of a theophylline slow-release tablet and a syrup form, when administered in multiple doses to healthy adult volunteers. The classification based upon releasing patterns is confirmed.
Subject: THEOPHYLLINE
PHARMACOKINETICS
PLASMA LEVELS
SLOW-RELEASE PREPARATION
HUMANS
Country: Brasil
Editor: Mem Inst Oswaldo Cruz
Rights: aberto
Date Issue: 1993
Appears in Collections:Unicamp - Artigos e Outros Documentos

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