Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/59013
Type: Artigo de periódico
Title: Papillary Squamous Cell Carcinoma of the Uterine Cervix, High-Risk Human Papilloma Virus Infection and p16(INK4a) Expression A Case Report
Author: Eleuterio, J
Giraldo, PC
Cavalcante, DIM
Goncalves, AKS
Eleuterio, RMN
Giraldo, HPD
Abstract: Background Papillary squamous cell carcinoma is a rare form of squamous cell carcinoma of the uterine cervix occurring in women in the sixth decade of life and is frequently misdiagnosed as high-grade intraepithelial lesion. Few reports with cytologic study have been performed, especially with cytology in liquid-based specimens. Case A 58-year-old woman who bad 8 gestations (no abortions) and mitral cardiopathy treated with coumarin medication was referred for transvaginal bleeding of 20 days' duration. Specular examination showed an exophytic, easily bleeding lesion occupying all of the uterine cervix and superior third of the vagina. Liquid-based cytology showed squamous cells, mostly basaloid but some bizarre or in fiber, with clearly atypical nuclei. Second-generation hybrid capture for high-risk human papillomavirus was positive, with a viral load of 404 relative light unit/positive control B, and the tumor expressed p16(INK4a). Conclusion This report adds farther experience with liquid-based cytology to the existing conventional and liquid-based cytologic findings, particularly in the Brazilian female population. (Acta Cytol 2009;53:188-190)
Subject: cervical cancer
cytologic techniques
human papillomavirus
neoplasms
p16(INK4a)
Country: EUA
Editor: Sci Printers & Publ Inc
Rights: fechado
Identifier DOI: 10.1159/000325122
Date Issue: 2009
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
WOS000264304100012.pdf459.81 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.