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dc.contributor.CRUESPUniversidade Estadual de Campinaspt_BR
dc.typeArtigo de periódicopt_BR
dc.titleMonitoring and Detection of Cytomegalovirus in Liver Transplant Recipientspt_BR
dc.contributor.authorMilan, Apt_BR
dc.contributor.authorSampaio, AMpt_BR
dc.contributor.authorGuardia, ACpt_BR
dc.contributor.authorPavan, CRpt_BR
dc.contributor.authorAndrade, PDpt_BR
dc.contributor.authorBonon, SHApt_BR
dc.contributor.authorCosta, SCBpt_BR
dc.contributor.authorAtaide, Ept_BR
dc.contributor.authorBoin, IFSFpt_BR
dc.contributor.authorStucchi, RSBpt_BR
unicamp.authorMilan, A. Sampaio, A. M. Guardia, A. C. Stucchi, R. S. B. Univ Estadual Campinas, Fac Med Sci, Campinas, SP, Brazilpt_BR
unicamp.authorPavan, C. R. Ataide, E. Univ Estadual Campinas, Gastroctr, Campinas, SP, Brazilpt_BR
unicamp.authorAndrade, P. D. Bonon, S. H. A. Univ Estadual Campinas, Diag Mol Infect Dis Lab Biomed, Campinas, SP, Brazilpt_BR
unicamp.authorCosta, S. C. B. Univ Estadual Campinas, Dept Internal Med, Campinas, SP, Brazil Univ Estadual Campinas, Liver Transplantat Unit, Campinas, SP, Brazilpt_BR
dc.description.abstractCytomegalovirus (CMV) is a p-herpesvirus. CMV infections are a common complication contributing to morbidity and mortality after liver transplantation. Among organ transplant recipients, CMV can reactivate from latency during the first 6 months. This prospective study performed from February 2008 to December 2009 examined liver transplant recipients during the first 6 months. Two methods were performed to detect CMV infections: antigenemia (AGM) and nested (PCR). Ninety-four patients, including 72 men (76.6%) and 22 women (23.4%) underwent liver transplantation during this period. We analyzed 575 samples including 465 for AGM and PCR. Forty-three (9.25%) showed positive AGM as detected 2 to 179 days posttransplantation with a mean of 50 days and a median of 35 days, and 93/465 (20%) showed positive PCR at 0 to 186 days posttransplantation with a mean of 31 days and a median of 38 days. Among the 43 antigenemia patients, 38 samples were positive for up to 5 cells 18 of which were PCR-positive. Five samples were positive with more than 5 cells, including 3 that were PCR-positive. Only 4.51% had AGM and were PCR-positive in the same sample. Despite only 9.25% (43/465) showing AGM, the current study suggested the utility of routine monitoring to detect early CMV infection among liver transplantation patients seeking to reduce morbidity and
dc.relation.ispartofTransplantation Proceedingspt_BR
dc.relation.ispartofabbreviationTransplant. Proc.pt_BR
dc.publisher.cityNew Yorkpt_BR
dc.publisherElsevier Science Incpt_BR
dc.identifier.citationTransplantation Proceedings. Elsevier Science Inc, v. 43, n. 4, n. 1360, n. 1361, 2011.pt_BR
dc.sourceWeb of Sciencept_BR
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)pt_BR
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)pt_BR
dc.description.sponsorship1Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)pt_BR
dc.description.sponsorship1Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)pt_BR
dc.description.provenanceMade available in DSpace on 2014-07-30T14:03:50Z (GMT). No. of bitstreams: 0 Previous issue date: 2011en
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