Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/57818
Type: Artigo de periódico
Title: MOLECULAR-IDENTIFICATION OF HEREDITARY PERSISTENCE OF FETAL HEMOGLOBIN TYPE-2 (HPFH TYPE-2) IN PATIENTS FROM BRAZIL
Author: GONCALVES, MS
FAHEL, S
FIGUEIREDO, MS
KIMURA, EJ
NECHTMAN, F
STOMING, TA
ARRUDA, VR
SAAD, STO
COSTA, FF
Abstract: The HPFH deletion type 2 was first described in a patient from Ghana and is characterized by a large deletion of approximately 105 kb extension. We report here the results obtained in studying a black Brazilian patient who presented an association of beta-thalassemia and HPFH type 2, using a PCR strategy for detection of the breakpoint region. This procedure allows a rapid molecular identification of this condition and is a reliable procedure for screening patients with a hematological picture of HPFH deletion types.
Subject: FETAL HEMOGLOBIN
THALASSEMIA
GLOBIN GENES
Editor: Springer Verlag
Rights: fechado
Identifier DOI: 10.1007/BF01682037
Date Issue: 1995
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
WOSA1995QR57100008.pdf312.31 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.