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dc.contributor.CRUESPUniversidade Estadual de Campinaspt_BR
dc.typeArtigo de periódicopt_BR
dc.titleCrystal-storing histiocytosis: a rare lesion in periapical pathologypt_BR
dc.contributor.authorPerez, DEDpt_BR
dc.contributor.authorSilva-Sousa, YTCpt_BR
dc.contributor.authorde Andrade, BABpt_BR
dc.contributor.authorRizo, VHTpt_BR
dc.contributor.authorAlmeida, LYpt_BR
dc.contributor.authorLeon, JEpt_BR
dc.contributor.authorde Almeida, OPpt_BR
unicamp.author.emailjorgeesquiche@yahoo.com.brpt_BR
unicamp.authorLeon, Jorge Esquiche Univ Ribeirao Preto UNAERP, Lab Patol Oral, Sch Dent, BR-14096090 Ribeirao Preto, SP, Brazilpt_BR
unicamp.authorda Cruz Perez, Danyel Elias Univ Fed Pernambuco, Oral Pathol Unit, Sch Dent, BR-50670901 Recife, PE, Brazilpt_BR
unicamp.authorBenevenuto de Andrade, Bruno Augusto Toral Rizo, Victor Hugo Almeida, Luciana Yamamoto Leon, Jorge Esquiche de Almeida, Oslei Paes Univ Campinas Unicamp, Piracicaba Dent Sch, Dept Oral Pathol, BR-13414903 Piracicaba, SP, Brazilpt_BR
dc.subjectCrystal-storing histiocytosispt_BR
dc.subjectPeriapical lesionpt_BR
dc.subjectOralpt_BR
dc.subjectImmunohistochemistrypt_BR
dc.subject.wosB-cell Lymphomapt_BR
dc.subject.wosMultiple-myelomapt_BR
dc.subject.wosLymphoproliferative Disorderpt_BR
dc.subject.wosPatientpt_BR
dc.subject.wosGlandpt_BR
dc.subject.wosLungpt_BR
dc.description.abstractCrystal-storing histiocytosis is a rare manifestation of plasma cell dyscrasia/monoclonal gammopathies and lymphoproliferative disorders, characterized by cytoplasmic accumulation of crystallized immunoglobulins in histiocytes. Nevertheless, some reported cases of crystal-storing histiocytosis raise the possibility that this lesion may also be reactive. Crystal-storing histiocytosis in the oral cavity is extremely rare; only one case affecting the tongue has been reported in the English-language literature. In this report, we discuss the case of a 38-year-old man who presented a persistent periapical lesion affecting the maxillary left lateral incisor. Histopathological analysis showed numerous crystal-laden histiocytes associated with a mild plasma cell infiltrate within a fibrous stroma. The plasma cells failed to show clonal light-chain restriction, and the patient had no associated hematologic disorder or systemic disease. Thus, this lesion was probably the result of hypersecretion of immunoglobulins by polyclonal plasma cells found in the periapical lesion. Crystal-storing histiocytosis should be considered in the differential diagnosis of periapical lesions. (C) 2012 Elsevier Inc. All rights reserved.pt
dc.relation.ispartofAnnals Of Diagnostic Pathologypt_BR
dc.relation.ispartofabbreviationAnn. Diagn. Pathol.pt_BR
dc.publisher.cityNew Yorkpt_BR
dc.publisher.countryEUApt_BR
dc.publisherElsevier Science Incpt_BR
dc.date.issued2012pt_BR
dc.date.monthofcirculationDECpt_BR
dc.identifier.citationAnnals Of Diagnostic Pathology. Elsevier Science Inc, v. 16, n. 6, n. 527, n. 531, 2012.pt_BR
dc.language.isoenpt_BR
dc.description.volume16pt_BR
dc.description.issuenumber6pt_BR
dc.description.initialpage527pt_BR
dc.description.lastpage531pt_BR
dc.rightsfechadopt_BR
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policypt_BR
dc.sourceWeb of Sciencept_BR
dc.identifier.issn1092-9134pt_BR
dc.identifier.wosidWOS:000311175400017pt_BR
dc.identifier.doi10.1016/j.anndiagpath.2011.05.004pt_BR
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)pt_BR
dc.description.sponsorship1Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.description.sponsorship1Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)pt_BR
dc.date.available2014-07-30T14:03:07Z
dc.date.available2015-11-26T18:05:31Z-
dc.date.accessioned2014-07-30T14:03:07Z
dc.date.accessioned2015-11-26T18:05:31Z-
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dc.identifier.urihttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/57488
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/57488-
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